MigreLief Category

2018 Amazing Wellness Awards – MigreLief-NOW

November 27th, 2018

And the winners are….

From the editors of Amazing Wellness Magazine, MigreLief-NOW was selected “Best New Herbal Remedy 2018.”

MigreLief-NOW, Akeso’s Health Sciences’ fast acting, “as-needed formula”  is an effective nutritional option for migraine and headache sufferers age 2+.  Not just for migraines and headaches, MigreLief-NOW can be taken daily for joint health and comfort.

Both MigreLief-NOW and MigreLief Original (daily maintenance formula) are sold in Vitamin Shoppes and Meijer stores nationwide.

Visit MigreLief.US store-finder for a store near you. 



Abdominal Migraine in Children – Safe Options

November 7th, 2018

Abdominal migraine is one of the most common causes of abdominal pain in children.  Although the pain will come and go, it is severely debilitating during a migraine episode, is very distressing for children. Chronic and recurring abdominal pain can have a drastic effect on a child’s overall quality of life and their school performance.

Abdominal pain in childhood accounts for 2-4% of office visits to the doctor and 50% of referrals to pediatric gastroenterologists.(1) Even though it is a well recognized type of pediatric migraine with specific diagnostic criteria under the International Classification of Headache Disorders, it is often underdiagnosed by both pediatricians and pediatric gastroenterologists.(2)

The diagnosis of abdominal migraine is much more prevalent in Europe than in the United States, because in the U.S. it is often misdiagnosed as U.S. doctors are still struggling to understand it.  Many doctors are only able to make an accurate diagnosis years after the abdominal migraines when the child becomes a teen and then develops classic migraines. Parents should be extra cautious as children could be subjected to unnecessary surgery if the condition is misdiagnosed.

What is an abdominal migraine?

Abdominal migraines are diagnosed in children who meet these criteria:

  • At least five attacks of abdominal pain that each last 1 to 72 hours
  • Dull pain around the belly button, moderate to severe in intensity
  • At least two of these symptoms: appetite loss, nausea, vomiting, pale skin

Other abdominal migraine symptoms may include, headache and sensitivity to light and sound.

Who gets abdominal migraines?

  • Children with a family history of migraines are at higher risk
  • Occurs slightly more often in girls than boys
  • Children who experience motion sickness are more likely to get abdominal migraines

Diagnosis of Abdominal Migraine

Abdominal migraines usually follow a pattern, same type of appearance, same time of day, and same duration with the symptoms going away completely between migraines.

Doctors may use ultrasound or endoscopy to check for other potential causes of your child’s stomach pain and evaluate your child’s medical history to determine a pattern.

Preventing Migraines
Help your child prevent migraines by discovering and avoiding their triggers if possible.  The triggers for abdominal migraines are similar for regular migraines:

  • Chemicals such as nitrites that are found in processed foods such as deli or processed meats, lunch meat, packaged sandwich ham, turkey, and chicken
  • Caffeine
  • Chocolate
  • Bright lights
  • Foods that contain monosodium glutamate (MSG) including Chinese food, dressings, seasonings, condiments, and many buffet foods in restaurants
  • Motion sickness
  • Fatigue or exhaustion
  • Flickering lights
  • Stress, worrying or being upset
  • Swallowing a lot of air
  • Lack of sleep

In many cases, taking proactive steps to prevent the migraine attacks can lead to less frequent attacks and a decrease in intensity and duration.

Where to start if your child was diagnosed with abdominal or classic migraines.

Consider a Safe & Gentle Nutritional Option…
The MigreLief Nutritional Regimen for Pediatric Migraines

Recommended by pediatric neurologists and headache specialists for almost 2 decades, MigreLief is a great place to start.  


Choose one of two MigreLief “daily maintenance” formulas;

Original MigreLief (age 12+) (caplets) or
Children’s MigreLief (age 2-11) (capsules)

The caplets may be crushed or capsules opened and mixed with food such as applesauce, yogurt etc. for children or teens that have difficulty swallowing pills.

Keep fast-acting MigreLief-NOW “as-needed” formula on hand at all times and take when ever needed for on-the-spot help.

The ‘Dream Team’ for Migraine Sufferers
Daily and As Needed formulas work well together.  While you are waiting for the daily chronic formula to kick in, you can take MigreLief-NOW as-needed.  All MigreLief formulas are drug free, safe, gentle and very effective.

Where to Buy? 
If purchased at MigreLief.com or by calling 1-800-758-8746 you can try risk free as there is a 90 Money Back Guarantee if you try MigreLief or Children’s MigreLief for 3 allows sufficient time for MigreLief to build blood levels for maximum effectiveness (each bottle is a one month supply).  If you are not satisfied for any reason, Akeso Health Sciences, will refund your purchase price.

You can also buy at the Vitamin Shoppe, Meijer stores or at independent pharmacies nationwide.  If your local pharmacy doesn’t stock it, you can ask them to order it and they can usually have MigreLief within 24 hours.

Questions?  Email:  HealthAdvisor@MigreLief.com or call 1-800-758-8746
Join MigreLief Fans on Facebook

Amazing Wellness Award 2018… MigreLief-NOW

Pumpkin and Pumpkin Seeds for Healthy Eyes, Heart, Skin, Hair, Weight Loss & More!

October 26th, 2018


Pumpkin Health BenefitsCommonly viewed as a vegetable, pumpkin is scientifically a fruit, as it contains seeds. Nutritionally it is more similar to vegetables than fruits. Pumpkin has a range of fantastic health benefits, including being one of the best-known sources of beta-carotene.

Eye Health:  Beta-carotene is a powerful antioxidant. It also gives orange vegetables and fruits their vibrant color.  The body converts any ingested beta-carotene into vitamin A.  Vitamin A is essential for eye health and helps the retina absorb and process light. One cup of pumpkin contains over 200 percent of most people’s recommended daily intake of vitamin A, making it an outstanding option for optical health.  Studies show that vitamin A can also strengthen your immune system and help fight infections. (1) (2)

High Antioxidant Content:  Free radicals are molecules produced by your body’s metabolic process. Though highly unstable, they have useful roles, such as destroying harmful bacteria.  However, excessive free radicals in your body create a state called oxidative stress, which has been linked to chronic illnesses, including heart disease and cancer. Pumpkins contain antioxidants, such as alpha-carotene, beta-carotene and beta-cryptoxanthin. These can neutralize free radicals, stopping them from damaging your cells.  Pumpkin may lower you risk of cancer. (3)  (4)

Heart Health:  Pumpkin contains a variety of nutrients that can improve your heart health.  It’s high in potassium, vitamin C and fiber, which have been linked to heart benefits.  For instance, studies have shown that people with higher potassium intakes appear to have lower blood pressure and a reduced risk of strokes which are both risk factors for heart disease. (5)

Weight Loss:  Pumpkin is rich in fiber, which slows digestion and keeps you feeling fuller longer.  It is low in calories as it is 94% water and contains only 50 calories per cup (245 grams).

Healthy Skin:  Pumpkin is great for the skin for many reasons.  Studies show that carotenoids like beta-carotene can act as a natural sunblock. (6)
Once ingested, carotenoids are transported to various organs including your skin. Here, they help protect skin cells against damage from harmful UV rays (7).
Pumpkin is also high in vitamin C, which is essential for healthy skin. Your body needs this vitamin to make collagen, a protein that keeps your skin strong and healthy. (8).
Moreover, pumpkins contain lutein, zeaxanthin, vitamin E and many more antioxidants that have been shown to boost your skin’s defenses against UV. (9) (10)

One cup of cooked pumpkin (245 grams) contains:

Calories: 49
Fat: 0.2 grams
Protein: 2 grams
Carbs: 12 grams
Fiber: 3 grams
Vitamin A: 245% of the Reference Daily Intake (RDI)
Vitamin C: 19% of the RDI
Potassium: 16% of the RDI
Copper: 11% of the RDI
Manganese: 11% of the RDI
Vitamin B2: 11% of the RDI
Vitamin E: 10% of the RDI
Iron: 8% of the RDI
Small amounts of magnesium, phosphorus, zinc, folate and several B vitamins.

When making pumpkin dishes… Don’t throw away the seeds!


Pumpkin SeedsPumpkin seeds were discovered by archaeologists in caves in Mexico back in 7,000 B.C.  North American Indian tribes were the very first to observe the dietary and medicinal properties of pumpkin seeds.  The nutrition in pumpkin seeds improves with age; they are among the few foods that increase in nutritive value as they decompose. Pumpkin seeds stored for more than five months increase in protein content. They can be consumed raw or toasted, plain or tossed in salads and other fresh or cooked dishes.  Containing a variety of nutrients ranging from magnesium to copper, protein and zinc, pumpkin seeds are extremely healthy and are a good source of B vitamins (thiamine, riboflavin, niacin, pantothenic acid, vitamin B-6 and folates), magnesium, iron and protein.  100 grams of pumpkin seeds contains about 30 grams of protein. They are the most alkaline-forming seed.


Heart Healthy:  Pumpkin seeds are a rich source of healthy fats, fibers and various antioxidants that are beneficial for the heart.  The high levels of essential fatty acids help maintain healthy blood vessels and lower unhealthy cholesterol in the blood.  Pumpkin seeds contain phytosterols, compounds that have been shown to reduce levels of LDL cholesterol.

Healthy Sleep:  Pumpkin seeds contain Serotonin, a neurochemical which promotes health sleep.  They are also high in Tryptophan, an amino acid that further converts into Serotonin in the body, to help you get a good night’s sleep.

Prostate Health:  High in zinc these seeds are useful for promoting men’s fertility and preventing prostrate problems. The oil in pumpkin seeds alleviates difficult urination that happens with an enlarged prostate.  Pumpkin seeds also have DHEA (Di-hydro epi-androstenedione) that helps reduce the chances of prostate cancer.

Stabilize Blood Sugar – Pumpkin seeds help improve insulin regulation in diabetics and decreases oxidative stress. These seeds are a rich source of digestible protein that helps stabilize blood sugar levels.

Hair Growth:  Pumpkin seeds consist of cucurbitin, a unique amino that may be responsible for hair growth. They also contain vitamin C that also plays a crucial role in hair growth. Apply pumpkin seeds oil on scalp to see the results or just consume a handful of them daily.

Bone Protection:  High in zinc, pumpkin seeds are a natural protector against osteoporosis, since zinc deficiencies can lead to higher rates of osteoporosis.
Pumpkin seeds are a good source vitamin E; they contain about 35.10 mg of tocopherol per 100 g.

Other benefits:  According to studies, pumpkin seeds prevent calcium oxalate kidney stone formation.  These seeds reduce inflammation and counter arthritis pain without the side effects of anti-inflammatory drugs.  They are also used in many cultures as a natural treatment for tapeworms and other parasites.

Take advantage of the abundance of pumpkins during the fall season and give your health a boost. Enjoy these healthy pumpkin recipes.



Pumpkin Smoothy

Tastes like pumpkin pie in a glass and will satisfy all your pumpkin cravings.  It combines pumpkin purée with almond butter, milk, delicious spices, and honey. It’s an excellent source of filling protein and fiber, plus it provides eye-helping beta-carotene. (Can’t get enough pumpkin?


1 cup low-fat milk
3/4 cup pumpkin puree
1 Tbsp almond butter
1/8 tsp ground nutmeg
1/4 tsp ground cloves
1 tsp vanilla extract
1 tsp maple syrup or honey
4 ice cubes

Directions:  Blend ingredients together, and enjoy! Serves 1.



Healthy Pumpkin MuffinsHEALTHY PUMPKIN MUFFINS (No Flour, Sugar Free, Oil Free, Dairy Free Gluten Free)

Healthy pumpkin muffins are a better-for-you alternative to traditional pumpkin muffins or pumpkin bread.
Gluten free, sugar-free, oil free, and dairy free. Your taste buds will love the healthy fall flavors.

Prep Time – 20 min
Cook Time – 20 min
Total Time – 32 mins
Servings: 14 muffins
Calories: 123  calories

2 1/2 cups old-fashioned oats (toasted & ground) * 9.3 ounces
3/4 cup old-fashioned oats (toasted, 2 Tbsp reserved for muffin tops) * 2.8 ounces
1 1/8 cups pumpkin puree * 10.7 ounces
2 large eggs (lightly beaten)
6 tbsp maple syrup (or honey)
3/4 cup canned coconut milk or dairy milk (full fat, skim or 1 %,)
2 tsp real vanilla
2 tsp baking powder
½ tsp baking soda
½ tsp salt
3 ½ tsp pumpkin spice (or 2 tsp cinnamon, 1 tsp ground ginger, 1/8 tsp allspice, 1/8 tsp ground cloves, and 1/4 ground nutmeg)
½ cup walnuts, raisins, dried cranberries, or chocolate chips (optional)

Preheat oven to 325. Place all oats on a baking sheet and toast until lightly browned, stirring once (about 4 to 6 minutes).
Let cool to room temperature. (If you are in a hurry you can skip this step and use plain old-fashioned oats, however the toasting adds flavor.)
Place 2.5 cups of oats in a food processor and blend/pulse until they reach a rough, flour like consistency.
Combine pumpkin puree, eggs, maple syrup, milk, and vanilla. Mix to combine.

Add both ground and unground oats to wet ingredients and allow to sit for 10-20 minutes (this allows the oats to soak and soften).
Add the rest of the ingredients and mix until just incorporated. (The batter will be very thick.)

Optional: Fold in approximately 1/2 c walnuts, raisins, chocolate chips, or dried cranberries.

Scoop batter into muffin tin, lined with muffin wrappers (makes 12-14 muffins). Fill the muffin tins 7/8 full.
Bake at 350 for about 23 – 25 minutes, a toothpick inserted in the center of a muffin should come out clean and the top of the muffin should feel firm.
Recipe Notes
Use parchment muffin liners or lightly spray liners lightly with oil to make the baked muffins easier to remove.


Pumpkin Soup

1 small pumpkin
1 onion
3 to 4 cloves of garlic (minced)
1.5 cups of vegetable broth
1.5 cups of coconut milk
1/4 tsp turmeric
Pinch of sea salt and black pepper
Olive oil (to brush on pumpkin flesh)
Pumpkin seeds and fresh rosemary (to garnish)

1. Preheat your oven to 375°F before cutting your pumpkin in half. Spoon out the strings and seeds, saving the seeds for roasting.

2. Using olive oil, brush the flesh of the pumpkin and place the halves skin-side up on a baking sheet. Bake for approximately one hour — a fork should be able to pierce the skin. When cooked, allow to cool.

3. On your stove top, saute garlic and onions until translucent — then add turmeric to toast slightly.

4. Add all remaining ingredients (pumpkin flesh, broth, coconut milk, salt and pepper) and bring to a simmer.

5. Once incorporated, use an emulsion blender to create a smoother consistency and continue cooking for 10 to 15 minutes.

6. When ready to serve, garnish with rosemary and pumpkin seeds. If you’d like to roast your own, simply toss seeds in olive oil and salt, baking for around 40 to 45 minutes, or until crispy and golden.


For more great recipes, visit BrenDid .com

5 Best Yoga Poses for Migraine Headache Relief

October 24th, 2018

It’s heartbreaking to see a friend, or loved one suffer a migraine attack but only those who suffer migraines can truly understand how traumatic and debilitating they are. Migraineurs have lost many precious moments to pulsating pain, vertigo, aversion to light and nausea to name just a few intolerable symptoms of migraine.  But there is hope.  In addition to avoiding various triggers when possible such as stress, hormone fluctuations, sleep disturbances, certain types of food, excessive use of caffeine, addressing migraines nutritionally at the cellular level and adding some healthy habits to your lifestyle such as yoga, can make all the difference.

Yoga for Migraine SufferersBENEFITS OF YOGA
More and more people are catching on to the benefits of yoga.  Not only does it increase flexibility, improve you balance, build muscle strength, improve you posture, and prevent cartilage and joint breakdown, it also increases blood flow, drains your lymphs and boosts immunity.  If that’s not enough to get you started with yoga, it can help regulate your blood pressure and adrenal glands, lower your blood sugar, help you focus, relax overall and release tension in your limbs, help you sleep and make you happy.

Yoga is also believed to reduce pain.  Yoga, meditation or a combination of the two is believed to reduce pain in people with arthritis, back pain, fibromyalgia, migraines and other chronic conditions.  Note:  While yoga is effective and most doctors today advise you to take up this form of workout, when it comes to migraines or disorders, always consult your physician as yoga is not an alternative to your physician’s advice.  Adding a cardiovascular activity such as walking or swimming and getting a good night’s sleep will help with reducing stress and is also very beneficial to migraine sufferers.



When going through the sequence of yoga poses (asanas), hold each pose comfortably for a few minutes while concentrating on relaxing and breathing, inhaling and exhaling, slowly and deeply.

#1  STANDING FORWARD BEND – Invigorates the nervous system by increasing blood flow and calms the mind.
Yoga for healing migraines• Standing with even weight through the feet, or weight very slightly forward onto the toes, keep the tailbone tucked under, allow the spine to bend forward.

• Tuck the chin gently in towards the chest, lengthen the back of the neck. Gently work the fingertips or palms towards the floor. Hold the pose, relax and breathe.




#2 CHILD’S POSE  – Calms down the nervous system, helps to increase the body’s parasympathetic state… decreasing stress and migraines.

Yoga for healing migraines

• Start on your hands and knees (tabletop position).

• Bring your legs all the way together, then sit your hips back onto your heels with your toes together, letting you knees spread apart wide,

• Stretch your trunk and arms forward and rest your forehead on the floor as you lower your chest onto your thighs. Close your eyes and relax for a few seconds and don’t forget to breathe.

• Reach your arms back along each side of your body, towards your feet, resting with your palms face up.

• Close your eyes, breathe and relax.



#3  CAT & COW – Improves blood circulation, relieve tension in the neck, shoulders, and upper back while increasing serotonin levels in the brain and relaxing the mind.
Yoga for Migraine Prevention

CAT:  Begin on your hands and knees (tabletop position).

• Center your hips over your knees and square your shoulders over your wrists.

• Inhale as you tilt your tailbone towards the sky, lowering your stomach towards the floor (cow pose).

• Arch your back and keep your neck long.  Relax and hold the position for a few seconds.
Yoga for Migraine Relief

COW:  Exhale as you round your spine, drop your head and tuck your chin (cat pose).

• Tighten your abdomen while keeping your chin to your chest.

• Breathe slowly and deeply while holding the pose for a couple of minutes.

• Switch between the cat and cow poses a few times while taking long deep breaths and slow exhales



#4  SUPINE TWIST – Stretches spine and relieves tension in the shoulders and back.

Yoga for Migraine Prevention

• Lie on your back with your knees drawn in towards your chest.

• Cactus your arms out by your sides with your palms facing up and parallel your shins to your mat, bringing your knees to 90-degree angles.

• Inhale, then exhale as you slowly lower your knees to the left side of your body.

• Hold for 8 breaths, then draw your knees back to center.

• Hug your knees into your chest for a breath, then twist to the right on an exhale. Hold for 8 breaths.



#5  CORPSE POSE – Rejuvenates the body by bringing it into a deep state of meditative rest.

Yoga for Migrane Relief

• You can end your yoga routine by lying down in this pose and relaxing.

• Lay on your back with legs and feet slightly apart and let feet fall out to the sides

• Rest arms away from your sides at a 30 degree angle with palms facing up.

• Close your eyes, and relax your entire body.

• Think happy thoughts!




Try increasing nutritional support if you are a chronic migraine sufferer by adding MigreLief dietary supplements to your daily regimen.

MigreLief Migraine Supplements






Created just for migraine sufferers, MigreLief® comes in 4 nonprescription nutritional formulas:

3 “daily maintenance”
Original MigreLief
Children’s MigreLief (age 2-12)
for menstrual migraine sufferers

“as-needed” formula
MigreLief-NOW for on-the-spot nutritional support.

The MigreLief® Nutritional Regimen for Migraine Sufferers:

MigreLief and MigreLief-NOWAction Step 1:  Choose one formula for daily maintenance and take daily.

Action Step 2:  Take MigreLief-NOW as-needed.

Action Step 3:  Live the life you love!

For more information, visit MigreLief.com, call 1-800-758-8746 or email healthadvisor@migrelief.com



**These statements have not been evaluated by the FDA and is not intended to treat, prevent, diagnose or cure any disease or medical condition.



Preventive and Acute Migraine Treatments

June 17th, 2018

Migraine HelpDebilitating migraines should not be a way of life but for many men, women and children suffering chronic migraines (many migraine days each month)… they, unfortunately, are.

Migraine treatments can be PREVENTIVE with the goal of stopping migraines before they start or ACUTE, treating the pain once it starts.

Often migraine sufferers find themselves running the gambit of preventive and acute treatments in search of migraine relief which can include, side-effect prone prescription drugs and over-the-counter medications. This can be gruelling, especially if the migraine medications you turn to, turn on you which can be the case with the chronic use of prescription and over-the-counter pain-killers including acetaminophen and NSAIDS such as aspirin, ibuprofen, naproxen. Not only can chronic overuse lead to “rebound” or medication overuse headaches, but it can also lead to kidney or liver damage, bleeding and an increase in cardiovascular risk.


There are many nutritional options that are known to have benefits for migraine sufferers. Three of the most effective are: RiboflavinMagnesium, and Feverfew.  This vitamin, mineral and herb are listed in the American Academy of Neurology’s Guidelines for Migraine Prevention.

Magnesium, Riboflavin (B-2) and Feverfew are combined into one dietary supplement:  MIGRELIEF® – TRIPLE THERAPY WITH PURACOL™.  (Online coupon Code:  MIGFREE4 for $4 off any migraine formula at MigreLief.com during Migraine Awareness month June 2018)

Providing THREE MECHANISMS OF ACTION TO HELP MAINTAIN NORMAL NEUROLOGICAL FUNCTION… MigreLief Original Formula, Children’s MigreLief (age 2-11) and MigreLief+M/menstrual were formulated to help migraineurs maintain normal cerebrovascular (blood vessels that supply the brain) tone and function by addressing the underlying nutritional deficiencies and imbalances that are common to many migraine sufferers. These deficiencies may lead to many dysfunctional processes in the brain.

Dysfunctional brain processes that can affect normal cerebrovascular tone and function include:  

  • Decreases in the Brains Cellular Energy Reserves.  Cells lose their energy production ability when the powerhouses of the cells (the mitochondria) become dysfunctional due to nutritional deficiency.
  • Excessive Platelet Aggregation – The clumping together of blood cells in the brain result in blood vessel changes (vasoconstriction and vasodilation)
  • Vasospasms (the contraction and dilation of blood vessels in the brain which occurs during migraines).

The combination of ingredients in MigreLief’s daily formulas; Original MigreLief, Children’s MigreLief and MigreLief+M (menstrual migraines)  help to maintain normal cerebrovascular tone and function.


Action Step 1:  Chronic Migraine Sufferers – Choose a Daily Maintenance Formula and Take Daily

MigreLief Original – Age 12-Adult use daily
Children’s MigreLief – Age 2-Adult use daily
MigreLief+M – Women with Menstrual Hormonal Migraines use daily

Action Step 2:  Take MigreLief’s “As-Needed” Migraine Formula On-The-Spot

MigreLief-NOW – Age 12-Adult, use as needed (dose for children is 1/2 adult dose stated on the label)

Important Reminder:   MigreLief daily formulas for chronic migraine sufferers may take 3 weeks to 3 months to build blood levels for maximum benefits so don’t stop taking it for at least 90 days. It will grow in effectiveness.  In the meantime, take your MigreLief-NOW as needed.

Money Back Guarantee – If purchased online at MigreLief.com or by calling 1-800-758-8746, Akeso Health Sciences (creator of MigreLief) offers a Risk-FREE money back guarantee if you try MigreLief for 3 months, sufficient time for maximum benefits.

WHERE TO BUY MIGRELIEF:  Store locator:  Visit MigreLief.US and type in your zip code for a store near you.  Independent pharmacies, Meijer, Vitmain Shoppe (Sept 2018), Medicine Shoppe, many Walgreens and hundreds of other stores sell MigreLief.  Visit MigreLief.com or call 1-800-758-8746

AMAZING FEEDBACK:  Visit MigreLief’s Facebook page for amazing unsolicited feedback by “MigreLief Fans” or ask questions.

Remember… It’s never too late to get your life back and to start living the life you love!


Butterbur (Petasites) for Migraine Headaches – Risks & Benefit Update

April 2nd, 2018

Butterbur for Migraines Risks vs. BenefitsIf you’re a Healthcare Professional recommending Butterbur (Petasites) to your patients, it’s important that you stay up-to-date on the latest information (see links at the end of this post).

As a chemist, medical researcher, and drug developer, four of the multitudinous questions you ask yourself when trying to decide if you should invest time and money into developing, using or recommending a particular compound are:

1.) How likely is it to be effective for the specific condition it’s being considered to treat?
2.) Are there any known or potential side effects or adverse events that could hypothetically occur?
3.) How do the answers to question #2 impact the risk/reward profile of the compound.
4.) Are there any other competing compounds that seem to have similar benefits with lower risk?

Over 15 years ago when we received multiple patents describing the use of a combination of two magnesium sources, high dose riboflavin, and special extracts of feverfew for prophylaxis of migraines, butterbur had not yet been shown in a randomized clinical trial to be effective for migraine prophylaxis.  Of course back in 2002, when the study by Lipton et al was published showing efficacy, I paid a lot of attention to butterbur and strongly considered creating an additional formula or adding it to our existing patented combination (now known as Akeso’s MigreLief with Puracol™).  Since the release of our Original MigreLief with Puracol™ we have formulated new products with additional ingredients, for example MigreLief+M for menstrual/hormonal migraines and MigreLief-NOW a fast-acting “as needed” formula, yet none of our products contain butterbur.

It was clear that the response to butterbur was favorable and by not offering it in one of our products we would be losing out on the additional revenue it was sure to generate. Nevertheless we decided never to use butterbur in any of our products. We could never get comfortable with the fact that we had to rely on a manufacturing process to consistently remove the Hepato-toxic and carcinogenic pyrolizidine alkaloids that are found in unprocessed butterbur.   Of course this was just our company’s decision and many companies and healthcare professionals used or recommended butterbur.  In fact, the American Academy of Neurology and the American Headache Society supported butterbur.

As healthcare professionals we all try to stay current on as much of the medical literature and reporting as possible.
In the last few years, much new information has surfaced regarding butterbur and we are providing you with links to that third party information to enable you to make the best decisions for your patients (see below).

To the Best of Health,

Curt Hendrix
Chief Scientific Officer,  Akeso Health Sciences



Michigan University of Medicine – Warning

Decemer 2017 – “Caution: Due to reports of liver toxicity, butterbur products are being voluntarily withdrawn from markets in the United Kingdom. Based on these reports, butterbur should not be used unless a doctor determines that the potential benefits outweigh the risks. People taking butterbur should be monitored by the doctor for adverse effects.”

Update on the efficacy and safety of Petadolex®, a butterbur extract for migraine prophylaxis – Dr. Joseph M. Prietto.
DovePress March 10, 2014

Migrane Preventative Butterbur Has Safety Concerns

“…Despite butterbur’s potential efficacy, doubts are increasing about the long-term safety of this supplement given the risk of liver damage and the lack of an actively regulated preparation. Due to the mounting concerns, the American Headache Society is currently evaluating a position statement cautioning against its use.” Migraine Preventative Butterbur Has Safety Concerns

Addressing the Long-Term Safety Aspects of Butterbur Therapy- A Call for Immediate Action
Andreas Schapowal, MD, PhD, DSc, Hon


MigreLief’s Super Blue Blood Moon Special – $4 OFF

January 30th, 2018

Visable before sunrise,  Wednesday, January 31st – Witness a Rare Lunar Phenomenon
If you live in the western part of North America, Alaska or the Hawaiian islands, set your alarm for early Wednesday morning on Jan 31st to witness 3 lunar phenomenons that have not happened simultaneously for 150 years:  A Supermoon, a Blue Moon and a Blood Moon.

A Blue Moon is the second full moon in a month with two full moons. The first full moon this month was on January 1st.

A Blood Moon is a totally eclipsed moon and usually looks red because the earth passes between the moon and the sun, and while the moon crosses through the shadow of the Earth it reflects all of Earth’s sunrises and sunsets.

If that isn’t enough… it is also a Supermoon which is when the moon is at its closest point to earth and appears to be 14% bigger and 30% brighter than normal.

This rare phenomenon is called a “Super Blue Blood Moon” and the last time all of these events happened at once was in 1866. That is the year Andrew Johnson was president, the second dome on the U.S. Capitol building was completed, the U.S. Congress passed the Civil Rights Act and approved the minting of a nickel 5-cent coin to replace the half-dime, and the year that the first bank robbery in U.S. history took place in daylight, which is also considered to be the first robbery by Jesse James and his gang.

So take advantage of this rare predawn vision.  Depending upon where you live, your viewing time and experiences will be different.  It will be easier to see in the west and more of a challenge to see in the east.  The eclipse begins 5:51 a.m. eastern time.  NASA will show a live link beginning at 5:30 a.m. eastern time.

And for MigreLief fans, we are offering a lunar special…

$4 OFF and any MigreLief formula or Calm & Clever memory/stress supplement.
Coupon Code;  LUNAR  Redeem at MigreLief.com or call 1-800-758-8746.

(Expires 2-4-18 (One per customer – may not combine specials)



December 25th, 2017

Blood Pressure Guidelines In November 2017, the American Heart Association redefined high blood pressure. Originally high blood pressure was defined as 140/90 or higher and if people could not get below those numbers through lifestyle changes, blood pressure medication was recommended.  The new definition of high blood pressure/hypertension has been lowered to 130/80 or above, thus by the stroke of a pen, the American Heart Association has declared that almost 50% of adults living in the United States are hypertensive.  This means that millions of people, who are not taking drugs for hypertension, may very likely be told by their doctors to start taking blood pressure medications.  The question is who are these new guidelines helping?

The drug companies will be laughing all the way to the bank with this new high blood pressure definition.  This is similar to what the drug companies convinced the doctors to do by reducing cholesterol guidelines so more people would be prescribed cholesterol drugs.  In my opinion, healthy people who don’t have any cardiovascular risk should totally stay away from these cholesterol drugs and should equally cautious about taking blood pressure medications, indicated by these new guidelines.

For sure the drug companies will benefit financially but what do these new tightened blood pressure goals mean to you the patient.  The study led to the change in guidelines was called the Sprint study and it looked at over 9,000 people who had blood pressure of 130/80 or higher.  Half of the 9,000 participants were given medication to lower their blood pressure to 120/80 or below.  The other half were given medication but less intensively to lower their blood pressure to 140/90 or below.  To determine the benefit of the more intensive treatment vs. the less intensive treatment, the outcomes of heart attack, or other acute coronary syndromes, stroke, heart failure or cardiovascular death were measured.  The study concluded that, 6.8% of the people whose blood pressure was lowered to 140/90 with the less intensive treatment suffered one of these cardiovascular events and 5.2% of the people whose blood pressure was lowered to 120/80 with higher doses of drugs or a combination of drugs suffered one of these cardiovascular events.

This amounts to an absolute difference of 1.6% between the 2 test groups.  What does this 1.6% difference mean in real life?   In effect it says…  If 62 new people are put on the more intensive medication to get to 120/80 or below as opposed to 140/90 or below, only 1 person out of 62 would be spared a cardiovascular event.  The other 61 people would get absolutely no benefit.  Even worse, while receiving no benefit, they would running the risk of side-effects and adverse events associated with these drugs such as dizziness, cough, erectile dysfunction, skin rash, loss of taste,  skin rash, fatigue, depression, insomnia etc.

The bottom line… If you are at high risk for a cardiovascular event, or have already had one or have angina, or atrial fibrillation or have a high familial risk, follow your doctor’s guidelines after you try lifestyle changes to get your blood pressure to wherever he or she suggests it be.  BUT if you are healthy and have not had a heart attack and do not have cardiovascular or familial risk factors and your blood pressure is above 120/80 but below 140/90, think twice about  taking any blood pressure medications if your physician suggests them  because of these new guidelines.   Instead, try losing some weight, reducing sugar intake, adding some additional moderate exercise and perhaps take an extra 400 mg/day of magnesium and these changes will more than likely get you where you want to be with no drugs required.

To the Best of Health,

Curt Hendrix, M.S., C.C.N., C.N.S.

Try this Healthy “Life Extension” Smoothie

December 3rd, 2017

I created the “Life Extension Smoothie” to provide some of nature’s most protective, healing and perfect nutrients to protect against those factors that cause aging and disease.

There are numerous health benefits to combining ground organic flax-seed, omega 3 & 6 essential fatty acids and blueberries in a delicious protein smoothie. These benefits are described below following the recipe.

Life Extension Smoothie


8 oz. (227g) fresh or frozen blueberries
2 Tbsp. (30g) ground flax seed powder
1 Tbsp. (15ml) Barlean’s Omega Twin* (organic flax & borage oils)
*May substitute another brand or just flax oil.
1 scoop MRM Natural Whey Protein Powder* (low carb and no sugar or artificial sweeteners)
*May substitute with any nutritious low/no sugar whey protein powder. A vanilla protein powder will add to it’s delicious taste.
16 oz. (474ml) water
1 tsp. (5g) cinnamon powder
4 ice cubes (adjust to preferred thickness)

Blending Instructions:

Add the ice, blueberries and flax seed powder first, then add the oil and cool water. Blend on low for about 10 seconds, then on high for a minute or more. Drink the first glass, then re-blend the remaining mixture for 20-30 seconds, and consume while still mixed and cold.


Flax Seed Powder – Flax is a blue flowering plant that has attracted the attention of medical researchers around the world. Not only is it a source of two different kinds of dietary fiber (soluble & insoluble, each with different health benefits), it is also a source of powerful, health-promoting Omega-3 essential fatty acids. Flax seed is the single highest source of “LIGNANS” which protect our body against cellular damage and unhealthy cellular changes. Flax seed has been studied for the following conditions: heart disease, prostate cancer, breast cancer, colon cancer, esophageal cancer, oral cancer, menopause, PMS, kidney disease, constipation, irritable bowel syndrome, diabetes, peptic ulcer, hemorrhoids, weight loss and mineral absorption.

Flax Seed Oil – Flax oil contains Omega 3 essential fatty acids, or EFA’s. These are the “anti-fat” fats that make foods like flax seed, and certain cold water fish like salmon, herring and mackerel so healthy. The EFAs are the good fats that fight the bad fats we get in our diet from junk food and processed foods which are almost impossible to avoid. The highest quantities of Omega-3 fatty acid, called alpha-linolenic acid (ALA), is present in flax-seed. ALA is the parent from which EFA and DHA (the healthy fish oils) are derived. ALA converts to compounds called prostaglandins. These compounds can be either inflammatory and anti-inflammatory. ALA converts to anti-inflammatory types of prostaglandins and since most degenerative disease all have inflammatory components, ALA is a welcome ally. In fact, studies have shown that ALA prevented platelets (red blood cells) from clumping together which can be a factor in heart attack. It has been known to increase the elasticity of heart arteries, and lowers the risk of heart attack and stroke. A study also showed that women who have breast cancer had very low levels of ALA in their breast tissue compared to women with healthy tissue.

Borage Oil – Borage is a plant whose flowers and leaves, as well as the oil from its seeds, are used as medicine. Borage seed oil contains a high content of the essential fatty acid known as gamma-linolenic acid (GLA). GLA is part of the inflammatory mediation process and therefore the oil might be expected to have an impact on a variety of diseases and inflammatory conditions such as rheumatoid arthritis, and atopic eczema. Combined with fish oil, borage seed oil has shown improvement in bone density in a study of elderly osteoporotic women. A study also concluded that GLA may hold promise for treatment of diabetic neuropathy.

Every cell in our body is enclosed by a cell membrane which plays a role in determining many cell functions, including what healthy or unhealthy things get in or out of our cells. Almost 25% of the cell membrane is composed of what should be healthy “phospholipids” (good fats). Unfortunately, because you get so very little of the good fats from sources like flax oil and borage oil, and so many of the bad fasts from the typical western diet, the body uses what it has (the bad fats, disease-causing trans and saturated fats) and incorporates the bad fats into these very critical cell membranes. The very nature, integrity and function of the cell membrane worsens, and a critical mechanism that we rely on to stay healthy and stay alive is seriously changed and compromised.

THE GOOD NEWS IS… by switching to a combination of flax-seed oil and borage oil (such as Barlean’s Omega Twin, or various brands of the individual oils combined), the body will begin to incorporate the “good fats” back into your cell membranes and re-establish cell membrane integrity and give you back the powerful protection that healthy cell membranes provide to our bodies. Matter of fact, the very process of AGING is associated with organic and biological changes in things like cell membranes. These EFA’s, by protecting cell membrane integrity, are combating some of the cumulative negative effects of aging and poor dietary habits.

Blueberries – All fruits and vegetables contain varying amounts of some powerfully protective and health promoting compounds called phytochemicals. One class of phytochemicals called “flavonoids” have an impressive range of heath benefits. Blueberries seem to have the most impressive combination of phytochemicals, especially flavonoids, compared to other fruits and vegetables. A 2017 double-blind, placebo-controlled trial has shown that blueberries can improve some aspects of cognition in older adults. Studies also suggest that blueberries can inhibit the growth of liver cancer, and can help preserve cognitive function in post-menopausal women and decrease their risk of developing Alzheimer’s disease. Blueberries also have amazing anti-oxidant powers that can protect you and your loved ones from most of the illnesses and diseases we all worry about.

We all know that we need oxygen to stay alive. But one of the byproducts resulting from the burning of oxygen is the production of potentially dangerous and unstable molecules called “FREE RADICALS.”  These free radicals are missing an electron and want to get that missing electron from somewhere in our bodies. They do this by attacking a healthy cell. This attack can cause the cell to die or to mutate… and neither option is a good choice!  Fortunately, both our bodies and certain foods can provide us with antioxidants that can neutralize these dangerous free radicals before they attack our cells. Because there are many different types of free radicals the real trick is to know which of the many antioxidants can neutralize as many of the different types of free radicals as possible. This is where the simple blueberry shines. The United States National Institutes of Health found that blueberries, which contain antioxidants, may act to protect the body against damage from oxidative stress, one of several biological processes implicated in aging and in the development of a number of neuro-degenerative diseases. Compared to 40 other fruits and vegetables measured for their anti-oxidant activity, the U.S. Department of Agriculture has ranked blueberries, by far and away the best.

Cinnamon – Proven health benefits of cinnamon are: high source of antioxidants, contains anti-inflammatory properties, protects heart heath, fights diabetes, helps defend against cognitive decline and protects brain function, may help lower cancer risk, fights infections and viruses, while protecting dental health and freshening breath naturally.

Whey Protein – Whey protein is considered a complete protein and contains all 9 essential amino acids and is low in lactose content. People commonly use it as supplementation, alongside resistance exercise, to help improve muscle protein synthesis and promote the growth of lean tissue mass. Whey protein enhances immune function, may lower blood pressure, treat type-2 diabetes, reduce inflammation, may be beneficial for inflammatory bowel disease, and enhance the body’s antioxidant defenses as well.

The “Life Extension Smoothie” makes it easy for people to incorporate these incredibly healthy ingredients and nutritional treasures into their diet effortlessly. Enjoy!

To the Best of Health,

Curt Hendrix, M.S., C.C.N., C.N.S.
Chief Scientific Officer, Akeso Health Sciences

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