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Migraine Headaches in Children – MigreLief Turning Frowns Upside Down

Under: Children's MigreLief, Children's MigreLief FAQs, Pediatric Migraine

Parents Choose Children’s MigreLief

Children’s MigreLief  is a gentle, and effective nutritional option for pediatric migraine sufferers ages 2-12. It is a the same effective “daily formula” as Original MigreLief (age 13-adult) with ingredient dosages adjusted to meet the needs of children.

MigreLief has been recommended by neurologists, pediatric neurologists, headache specialists and other healthcare professionals for over 2 decades.

One of the hardest things for a parent to do is to see their child in pain. Yet every day millions of parents must watch helplessly as their children suffer from debilitating migraine attacks often accompanied by symptoms of nausea, abdominal pain and vomiting. About one out of every 10 kids, or nearly 8 million children in the United States alone are plagued by what has become the most common acute and recurrent headache pattern experienced by children today.

So don’t wait.  Give your children the nutritional support they need to make a positive difference in their lives today.

The under-use of migraine prevention was discussed in a recent (Nat’l Public Radio) article stating “Researchers are finding that “migraines beget migraines,” therefore the mandate for all patients is clear:  Reduce the number of migraines.”  Andrew Charles, director of UCLA’s Headache Research and Treatment Program, states “The more migraines a patient gets, the more susceptible they become to having more,” adding that “There seems to be this sort of tipping point where patients go from having episodic headaches to having them really continuously and being in a state of constant sensory sensitivity.”  Charles and other researchers are investigating exactly why and how that “tipping point” occurs.Safe, gentle, nutritional option for pediatric migraine sufferers without  disruptive side-effects.

Children’s MigreLief  Triple Therapy with Puracol™

  • – Same effective formula as Original MigreLief with ingredient doses adjust to meet the needs of children age 2 through 12.
  • – Specifically formulated to help maintain normal cerebrovascular tone and function in children who persistent migraine (many migraine days each month).
  • – Contains three ingredients (a vitamin, a mineral and a plant)-  Magnesium, Riboflavin (B-2) and   Feverfew
  • – All three ingredients have been shown in clinical studies to benefit migraine sufferers including children age 2+.

MigreLief’s Triple Therapy with Puracol™ provide 3 mechanisms of action working at the cellular level to address dysfunctional brain processes that can lead to migraines when triggered.  These dysfunctional brain processes include:

  • – Excessive platelet aggregation (clumping together of blood platelets in the brains blood vessels)
  • – Vasospasms (changing sizes of blood vessels/dilating & constricting)
  • – Depletion of cellular energy reserves (dysfunctional mitochondria, the powerhouses of cells)

The Science of MigreLief


Many recurring migraine sufferers resort to taking prescription medicines such as triptans when a migraine gets out of control. These medicines are abortive drugs used “acutely.”  This means you take them when you already have a migraine you hope to stop. These drugs do not prevent migraines from occurring in the first place.

In fact, not only do they not prevent migraines, the general consensus among researchers and clinicians is that on-going regular use of triptan drugs  increase the total number of migraines.   OTC drugs containing caffeine such as Excedrin Migraine (acetaminophen, aspirin, and caffeine) are also notorious for causing rebound headaches if taken too often.

It is far better to nip migraines in the bud as opposed to treating the pain and other symptoms of migraine forever.  Knowing your child’s migraine triggers (lack of sleep, certain foods such as aged cheese, caffeine etc.) and avoiding those triggers can go a long way toward migraine prevention.


Magnesium (oxide & citrate) – 180 mg/day
Riboflavin (B-2) – 200 mg/day
Puracol™ Feverfew*  – 50 mg/day

*Puracol™ is Akeso’s proprietary blend of the plant feverfew, both whole leaf and extract processed to maximize all beneficial phytochemicals

Contains no yeast, milk, corn, wheat, gluten, soy, sodium, salt, sugar, flavorings, preservatives, or artificial colors).  Contains NO Butterbur.

NOTE:  There are no specific side-effects associated with the ingredients in Children’s MigreLief and childhood use. Dietary supplements of any kind can cause gastrointestinal upset in susceptible users. Riboflavin is a water soluble vitamin and may turn your child’s urine bright yellow. This is normal. MigreLief  does not interfere with prescription or OTC medications a child might be taking.


Magnesium is a nutritional supplement with numerous effects that support cerebrovascular tone.

These include:

1) Inhibition of platelet aggregation
2) Interference with synthesis, release, and action of inflammatory mediators
3) Direct alterations of cerebrovascular tone
4) Inhibition of vasospasm
5) Stabilization of cell membranes

Some migraine sufferers with poor cerebrovascular tone have been found to have low brain levels of magnesium. Recommended daily dosages of magnesium typically range from 200 to 600 mg to compensate for this deficiency, far above what’s found in most multi-vitamins. Several double blind placebo controlled studies have demonstrated that oral magnesium is very beneficial to migraine sufferers.

Riboflavin (vitamin B-2) is a precursor of flavin adenine dinucleotide (FAD). This coenzyme is an important component of the electron-transport chain. A deficiency of mitrochondrial energy reserves has been observed in some persons exhibiting poor cerebrovascular tone. This defect may theoretically be corrected by a compound such as riboflavin that improves the activity of the electron-transport chain.

MigreLief provides 400mg of Riboflavin, which is significantly higher than most multi-vitamins or B-complex products. Multiple studies have demonstrated that high dose riboflavin is very beneficial to adults and children suffering migraines.

Puracol Feverfew
Commonly recommended for its ability to support cerebrovascular tone, feverfew (Tanacetum Parthenium) is rich in compounds known as sesquiterpene lactones. One of the more important of these compounds may be parthenolide, which represents 85% of the sesquiterpene lactone content in feverfew. Some scientific studies indicate that while parthenolide may be important there may very well be other phytochemicals in feverfew that are as of yet unidentified and play a role in its effectiveness.

Some studies of extracts of feverfew containing parthenolide yielded no significant benefits. This led researchers to believe that certain of the unidentified phytochemicals may have been left behind during the extraction process. The ideal solution would be a non-extracted feverfew product that naturally contained high levels of parthenolide and kept all of the other naturally occurring phytochemicals as well. For this reason Puracol Feverfew, AKESO HEALTH SCIENCE’S proprietary non extracted plant source for feverfew maximizes all naturally occurring phytochemicals. Studies have shown the benefits of feverfew on long-term cerebrovasular tone in multiple human studies.



While many people experience benefits as early as 3 weeks, if you are trying Children’s MigreLief (age 2-12) or MigreLief Original (age 13-adult) for the first time, we suggest giving it 3 months which is sufficient time for the ingredients to build up, kick in and do their job.  You should notice MigreLief growing in effectiveness over this time period.



MigreLief-NOW:  FAST-ACTING MIGRELIEF FORMULA to keep on hand at all times.Fast-Acting "As-Needed" Formula for Migraine Sufferers Age 2 through Adult
While you are waiting form MigreLief (daily formula) to kick in, keep MigreLief-NOW “as-needed” formula on hand at all times and take when needed for neurological comfort.  MigreLief-NOW is fast-acting nutritional support for adults and children age 2+ who need help on-the-spot.  See back of label for usage by age.


FOR MORE INFORMATION about MigreLief supplements  or other Akeso products, visit

Questions about MigreLief: Email


We  are so confident MigreLief or Children’s MigreLief will make a huge difference in your child’s life, we offer a 100% money back guarantee of your purchase price if you are not satisfied for any reason after trying MigreLief for the recommended 90 days.


All of Akeso’s condition-specific dietary supplements are formulated by migraine supplement pioneer scientist Curt Hendrix, the Chief Scientific Officer of Akeso Health Sciences.  The unique and synergistic MigreLief formulation received two U.S. patents with a third patent pending.  Curt has dedicated his life to the research and development of safer medicines based on herbal and natural compounds.  He was the principal scientific investigator for multiple NIH studies examining natural supplements for Alzheimer’s disease.

Official Website Children’s MigreLief