MigreLief Blog

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July 31, 2016 | 7:00am

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May not combine with other offers or specials. One coupon per order. Orders of 3 bottles or more qualify for FREE worldwide shipping.

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Migrelief 4 formulas

Butterbur (Petasites) for Migraine Headaches – Risks & Benefit Update

July 22, 2016 | 9:43am

Butterbur for Migraines Risks vs. BenefitsIf you are a healthcare professional recommending Butterbur (Petasites) to your patients, it is important that you stay up to date on the latest information (See links at bottom of page).

As a chemist, medical researcher, and drug developer four of the multitudinous questions you ask yourself when trying to decide if you should invest time and money into developing, using or recommending a particular compound are:

1- How likely is it to be effective for the specific condition it’s being considered to treat?
2- Are there any known or potential side effects or adverse events that could hypothetically occur?
3- How do the answers to question #2 impact the risk/reward profile of the compound.
4- Are there any other competing compounds that seem to have similar benefits with lower risk?

Over 15 years ago when we received multiple patents describing the use of a combination of two magnesium sources, high does riboflavin and special extracts of feverfew for prophylaxis of migraines, butterbur had not yet been shown in a randomized clinical trial to be effective for migraine prophylaxis.  Of course back in 2002, when the study by Lipton et al was published showing efficacy, I paid a lot of attention to butterbur and strongly considered creating an additional formula or adding it to our existing patented combination (now known as Akeso’s MigreLief with Puracol™).  Since the release of our Original MigreLief with Puracol™ we have formulated new products with additional ingredients, for example MigreLief+M for menstrual/hormonal migraines and MigreLief-NOW a fast-acting “as needed” formula, yet none of our products contain butterbur.

It was clear that the response to butterbur was favorable and by not offering it in one of our products we would be losing out on the additional revenue it was sure to generate. Nevertheless we decided never to use butterbur in any of our products. We could never get comfortable with the fact that we had to rely on a manufacturing process to consistently remove the Hepato-toxic and carcinogenic pyrolizidine  alkaloids that are found in unprocessed butterbur.    Of course this was just our company’s decision and many companies and healthcare professionals used or recommended butterbur.  In fact the American Academy of Neurology and the American Headache Society supported butterbur.

As healthcare professionals we all try to stay current on as much of the medical literature and reporting as possible.
In the last few years, much new information has surfaced regarding butterbur and we are providing you with links to that third party information to enable you to make the best decisions for your patients. (see below)

To the Best of Health,

Curt Hendrix
Chief Scientific Officer,  Akeso Health Sciences


Update on the efficacy and safety of Petadolex®, a butterbur extract for migraine prophylaxis – Dr. Joseph M. Prietto.
DovePress March 10, 2014

“Migrane Preventative Buterbur Has Safety Concerns”

“…Despite butterbur’s potential efficacy, doubts are increasing about the long-term safety of this supplement given of the risk of liver damage and the lack of an actively regulated preparation. Due to the mounting concerns, the American Headache Society is currently evaluating a position statement cautioning against its use.”


What is the difference between the Quantum brand and the Akeso brand of Migrelief?

July 16, 2016 | 12:05am

“What is the difference between Akeso MigreLief formula and the Quantum MigreLief formula?” – This is a question we have been asked often over the years and up until June 2016, the answer would have been, “Nothing”. Akeso Health Sciences, the formulator and patent holder of the chronic migraine formula known for the last 15 years as “MigreLief” gave Quantum limited distribution rights to sell Akeso’s patented formula under the Quantum label. Akeso Health Sciences is now the exclusive distributor of their patented formula, Magnesium, Riboflavin and Puracol™ Feverfew.

Please note: At this time, there may still be bottles of Quantum MigreLief containing Akeso’s patented formula (MigreLief with Puracol™) in stock at various resellers that have yet to sell off their remaining supply. However, Quantum is now distributing a new formula under the name “MigreLief” that does not contain the same patented formula.

If you are looking for the original patented MigreLief formula of the past 15 years, be sure to LOOK FOR THE AKESO AND PURACOL™ BRANDING.  The patented formula continues to be sold exclusively under the Akeso label (see image below), online at MigreLief.com and many other online vendors, or by calling 1-800-758-8746. You may also visit our store-finder at MigreLief.US and type in your zip code to locate the store nearest you selling Akeso’s MigreLief Original formula with Puracol™.


Akeso MigreLief with Puracol™ – Original Patented Formula

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