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The Science of MigreLief Supplements for Migraine Sufferers

December 27th, 2018

Magnesium, Riboflavin and Puracol™ Feverfew – Triple Therapy for Migraine Sufferers

Migraine is a neurological disease with symptoms ranging from severe head pain, visual disturbances, vertigo, nausea, and sensitivity to light, sound or smell. Approximately 37 million Americans suffer migraines which can last from hours to days. For many men, women and children, migraine attacks not only disrupt quality of life, they are debilitating. Nutritional deficiencies, inflammation and vasospasm can independently and together contribute to migraine occurrence, frequency and intensity.

The dysfunctional brain processes that have been shown to be present in migraine sufferers during migraine attacks include:

• Excessive platelet aggregation resulting in vasospasms due to serotonin release.
• Decrease in the brain cell’s mitochondrial energy reserves.

The ‘Triple Therapy’ combination of Magnesium, Riboflavin and Feverfew have been proven in double blind placebo-controlled studies to be beneficial to migraine sufferers. This combination helps maintain healthy cerebrovascular tone and function while promoting healthy mitochondrial energy reserves.

Magnesium
Studies have shown migraine sufferers with poor cerebrovascular tone have low levels of magnesium. Magnesium is a natural mineral that is necessary for healthy bodily function as it promotes heart health, stabilizes blood pressure, regulates nerve and muscle function and builds bone, DNA and protein. Magnesium is intimately involved in the control of N-methyl-D-aspartate (NMDA) glutamate receptors which play an important role in pain transmission in the nervous system and in the regulation of cerebral blood flow. Magnesium ions plug the NMDA receptors which renders calcium unable to exert its vasodilatory effects.

Magnesium has numerous effects that support cerebrovascular tone and function including the following mechanisms of action:

• Inhibition of platelet aggregation
• Interference with synthesis, release and action of inflammatory mediators
• Direct alterations of cerebrovascular tone
• Inhibition of vasospasm
• Stabilization of cell membranes.

Riboflavin (Vitamin B-2)
Research has shown that a mitochondrial defect may reduce an individual’s threshold to migraine triggers and lead to migraines. A deficiency of mitrochondrial energy reserves has been observed in many people exhibiting poor cerebrovascular tone. Riboflavin is a water-soluble vitamin that helps the body convert food to energy. It is a precursor of flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN ) which unlike CoQ10 are involved in all three cellular energy production processes; glycolysis, krebs cycle and electron transport. At the proper dose, riboflavin helps maintain healthy mitochondrial energy reserves which is very beneficial to migraine sufferes.

Feverfew
The herb feverfew (Tanacetum Parthenium) has been recorded as a medicinal remedy for millennia. Commonly recommended for its ability to support cerebrovascular tone, feverfew is rich in compounds known as sesquiterpene lactones and glycosides. While much of the feverfew research focuses on parthenolide, a type of sesquiterpene lactone, Akeso feels this is myopic and ignores studies that show feverfew benefits when the parthenolides are removed. While parthenolide may help, the presence of a full spectrum of other feverfew phytochemicals that Akeso has identified is what really makes the difference.

Scientific studies show feverfew inhibits platelet aggregation and the release of serotonin from platelets and polymorphonuclear leukocyte granules. Feverfew also inhibits pro-inflammatory prostaglandin synthesis and the release of arachadonic acid.

MigreLief Triple Therapy with Puracol™
Migrelief for Migraine Relief

The unique MigreLief ‘Triple Therapy’ formulation received 2 U.S. patents with a third patent pending. The world class efficacy of MigreLief is, for the most part, a result of the research and investment in feverfew chemistry that Akeso Health Sciences pioneered leading to the development of Puracol™ feverfew. The unique profile of the phyto chemicals present in Puracol™ feverfew go beyond industry standards and give MigreLief users a significant advantage in achieving the results they seek.

4 Nutritional Options
Migraine Relief

Recommended by neurologists and headache specialists for two decades, Akeso’s line of MigreLief supplements include four nutritional options: Three daily maintenance formulas for chronic migraine sufferers; MigreLief Original, Children’s MigreLief (age 2-12) and MigreLief+M (menstrual migraine) PLUS an “as needed” on-the-spot formula, MigreLief-NOW.

All of Akeso Health Sciences’ condition-specific dietary supplements are formulated by Chief Scientific Officer, Curt Hendrix, M.S., C.C.N., C.N.S. an authority on natural remedies. He has been a principal scientific investigator for multiple National Institutes of Health studies researching the effects of nutritional supplements on Alzheimer’s disease.

For more information visit MigreLief.com or email HealthAdvisor@MigreLief.com

 

References: The Journal of the American Nutraceutical Association. Vol; 6, No. 4, Fall 2003. Magnesium, Feverfew, and Riboflavin: Therapeutic Use in Migraine Prevention.
Andrea Cohen, M.D., Lisa Colodny, Pharm D, Nordia Bryan, PharmD, Samantha Luong, PharmD, Jennifer Rooney, PharmD.

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Non-Prescription Fast Acting “MigreLief NOW” – All New MigreLief Formula for Migraine & Headache Sufferers

August 4th, 2015

SUFFERING WITH MIGRAINE PAIN AND NEED HELP NOW?

Do you take pain medication or off-the-shelf headache medication to help manage your migraine pain just so you can make it through the day? You now have a safe drug-free fast-acting alternative!

INTRODUCING “MigreLief-NOW An all new dietary supplement that can be taken AS NEEDED for FAST-ACTING cerebral support during difficult times.

For migraine sufferers, the battle against migraines seems endless and it takes everything they’ve got to shore up and courageously battle on.  Life’s obligations don’t cease when one feels down for the count as so often pressure and worry compound the pain.

Towards our goal of empowering migraine and headache sufferers with an arsenal of nutritional options for battling migraines, Akeso Health Sciences is pleased to announce the release of our newest non-prescription dietary supplement, MigreLief-NOW – formulated to provide on-the-spot, fast-acting nutritional support when a migraine or headache sufferer needs it most… NOW!  

 

A Note from Curt Hendrix, M.S., C.C.N., C.N.S., – Chief Science Officer, Akeso Health Sciences, and creator of MigreLief

WHY MULTIPLE MIGRELIEF FORMULAS?

4 migraine-relief formulas As a migraine and headache sufferer, you may wonder why Akeso offers several different nutritional migraine supplement formulations to help you maintain healthy cerebrovascular tone and function.

We are all uniquely different in how we respond to things, be it food, movies, beauty, humor, medicines and even supplements.  THERE IS NO “ONE SIZE FITS ALL” IN MEDICINE OR EVEN NUTRITION!

For example, some people may do well on a low carbohydrate, high protein diet while others may develop dyspepsia, (stomach upset), fatigue or a host of other side-effects.

Certainly this is the case for prescription medicines that physicians offer to their patients.  Quite frequently a physician may have a patient switch antibiotics because the first one didn’t work or caused intolerable side-effects.

We are fortunate that physicians have options from which to choose when one drug just doesn’t agree with or work for someone. This applies in all areas of medicine and that’s why multiple drugs exist for the same condition, disease or illness such as high cholesterol, depression, blood pressure, asthma, diabetes or even cancer, just to name a few.

The same logic applies to dietary supplements.  Even though a majority of MigreLief users experience significant benefits with the patent protected MigreLief formulas, some sufferers still need additional help and options to get their lives under control.

This is why we never stop researching at Akeso Health Sciences.  We keep asking ourselves “How can we do better?”  “How can we help the people who still need help?”

It is for this reason that we have developed and added MigreLief-NOW to the MigreLief line of migraine supplements.

MigreLief–NOW, is a new option for those unpredictable times when fast-acting, on-the-spot support is needed to help maintain normal and healthy cerebrovascular function.

INGREDIENTS:  Puracol Feverfew, Aflapin Boswellia Serrata, Cerevasc Ginger and Magnesium.  Kosher/Vegetarian.

Does NOT contain:  Aspirin, caffeine, yeast, wheat, corn, milk, gluten, soy, salt, artificial colorings or flavorings.  Kosher/Vegetarian.

These ingredients have been shown in human clinical studies to have numerous health benefits including benefits for migraine and headache sufferers

RECOMMENDED USAGE:  Take 2-4 MigreLief-NOW capsules as needed with food, at the first sign of discomfort. Wait 2 hours and if needed, 2 more capsules can be taken.

Half of the adult dose can be given to children between the ages 2-11.

MigreLief-NOW can be taken at any time with any other migraine treatments, including all other MigreLief formulas.

Note:  If you are a chronic migraine sufferer (several migraines each month,) MigreLief-NOW is not meant to replace daily MigreLief  maintenance formulas.

In addition to taking MigreLief-NOW as needed during difficult periods, if you are currently using a MigreLief daily formula; MigreLief Original Formula, Children’s MigreLief or MigreLief+M, and feel you need additional daily support, you may add 2 MigreLief-NOW capsules a day to your morning dose (1 for children between age 1-11).

Read more about MigreLief-NOW and order directly online,

or use our STORE LOCATOR to find a store near you!

Follow our blog for health tips and coupons.

 

You can count on Akeso to be at the leading edge of research and innovation when it comes to safe and effective nutritional options for migraine and headache sufferers.

To the Best of Health, 

Curt Hendrix M.S., C.C.N.,  C.N.S.

 

 

 

 

 

 

 

 

 

SUFFERING WITH IRRITABLE BOWEL SYNDROME? SOME NATURAL MEDICINES THAT MAY HELP AND A NEW DIET FROM EUROPE FOR IBS SUFFERERS

November 12th, 2011

IBS (Irritable Bowel Syndrome) is experienced by at least 1 in 5 people. Though not dangerous, it can cause significant pain and discomfort.  Its cause is not known and it should not be confused with or is it related to IBD (Inflammatory Bowel Disease) which includes both ulcerative colitis and Crohn’s disease.

Symptoms of IBS range from:

  • ·         Diarrhea and or constipation (which sometimes can alternate)
  • ·         Bloating
  • ·         Gas pains
  • ·         Backache
  • ·         Fatigue

There are a number of natural remedies which work for some IBS sufferers and not others. Sometimes it is a matter of trial and error as to which, if any of these options may help you:

Psyllium: 3 grams, 3 times a day can help to normalize bowel activity in some sufferers and has been shown to reduce IBS symptoms in placebo controlled trials.

Lactase – The enzyme that helps to digest the milk sugar, lactose, can help lactose intolerant sufferers to reduce their IBS symptoms.

Peppermint Oil Softgels – Either alone or in combination with caraway oil, softgels containing either .3ml or 50 mg. of each oil have been shown in placebo-controlled studies to alleviate symptoms of IBS.

Activated Charcoal – Has been shown in blinded, placebo-controlled studies to reduce up to 60% of IBS symptoms in some patients.

Probiotics – Several recent studies have shown that daily consumption of probiotics have been effective in reducing IBS symptoms in sufferers.

Amongst the newest research reported for alleviating IBS symptoms is the use of a novel elimination diet called the Low Fodmaps Diet.  This diet is gaining major support in Europe where it was developed.

It has long been thought that certain dietary components can lead to IBS. The Low Fodmaps Diet identifies a protocol for eliminating those foods that are thought to be the most problematic. For more information on the Low Fodmaps Elimination Diet visit the following link:   “When Everyday Foods are Hard to Digest”

Best of Health,


Curt Hendrix, M.S., C.C.N., C.N.S.