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It’s the 4th of July. Make Sure Only Fireworks Explode and Not Your Head!

Migraine Relief - MigreLiefThis 4th of July… be prepared.  Keep MigreLief-NOW on hand at all times in case of an emergency and take at the first sign of discomfort.

The 4th of July is fun for most everyone. But certain aspects of what we do on the 4th can bring on a migraine attack.

Avoid common migraine triggers:

1- Barbequed meats, cheeses, chips, dips, pickles & olives, meat tenderizers, diet sodas – The chemicals found in these ingredients have all been associated with migraines

2- Loud Noises – Don’t get to close to the fireworks and cover ears if sensitive

3- Bright Lights – Consider wearing sunglasses when watching the fireworks

4- Alcohol – When combined with all of the above can bring on migraine in many people. So stick with water, fruit juice, coffee, or if available, beverages sweetened with stevia or erythritol.

What is best to eat?

Burgers without tenderizers, prepared with basic seasonings like salt and pepper. grilled chicken with vegetables, and fruit salads are healthier substitutes….don’t forget to drink plenty of water.

Don’t for get that Akeso Health Sciences, fast acting migraine formula, MigreLief-NOW is great to keep on hand during emergencies.  Adults should take 2-4 capsules at the first sign of distress (children age 2-11 take 1/2 the adult dose) and enjoy your holiday.

Hopefully these hints will keep you independent of migraines on Independence Day!


Curt Hendrix, M.S. C.C.N., C.N.S


Avoid Spring Migraines

The brain of migraineurs likes consistency. Many factors change with the seasons and influence migraines.   Changes in sleep patterns, light, air-pressure, temperature, humidity, and fragrances, can all increase the the frequency and tendency of migraines.

Beware of hotter days. A team of researchers at Harvard found that an increase in temperatures occurred 24 hours before increases in admissions to emergency rooms for treatment of migraines.   There is not much a patient can do to control the weather or avoid warm temperatures or changes in barometric pressure, therefore it is important to be vigilant about managing other triggers such as sleep and diet.  Avoid well known food triggers, and drastic changes in your sleep pattern if you can.  It  is also very important to stay well hydrated and to avoid strenuous outdoor activities or exercise during times of the day when it’s excessively warm or humid.

Spring is allergy season, and for many people sinus or allergy headaches can lead to migraines.

Tips to avoid “Spring” migraines:

1.  To avoid airborne allergens in your home, clean or change A/C filters
2.  If you are allergy prone, make sure your allergy meds are handy.
3.  With higher temperature, dehydration occurs even if we don’t feel dehydrated. Dehydration is a big cause of migraines. Drink lots of water

4. Stick with a sleep schedule, try to got to bed at the same time as much as possible and determine what number of hours is best for you. Both too little and too much sleep can increase migraine risk.

5. Light (photophobia) is a major contributor to migraine risk. Purchase a polarized, high grade pair of sunglasses and wear a hat with a brim to keep out even more light.

6. Be careful of new fragrances that you introduce not only in perfumes but moisturizers as well.

Follow these tips, use your Migrelief daily, keep fast acting MigreLief-NOW on hand for emergencies, and enjoy the fun and beauty of Spring.

To the Best of Health,


Curt Hendrix, M.S., C.C.N., C.N.S.


Related Article – “The Anti-Migraine Diet”

Menstrual Migraines in Adolescents

Many adult women who suffer from chronic migraine headaches find that many, if not most of their headaches occur between 2 days before menstruation and 2-3 days after menstruation. These migraines are referred to as “menstrual” or hormonally related migraines.

Recently researchers at Cincinnati’s Children’s Hospital completed a study analyzing what percentage of adolescent, menstruating young women experienced “menstrual” or “hormonally” related migraines.

It was found that out of the 891 adolescent girls studied, 50% experienced a headache during their first period upon entering puberty and almost 40% of these adolescents continued to experience migraines just before or just after their periods.

These migraines are brought about by both the hormonal shifts that occur during menstruation as well as changes in blood sugar levels. They are often accompanied by PMS symptoms of bloating, breast pain, irritability, cravings, acne, poor sleep and anxiety, as well.

Correcting these imbalances can reduce or eliminate both migraines and many of the symptoms of PMS.

Our own clinical observations indicate that addressing hormonal shifts without also balancing blood sugar levels leads to less comprehensive benefits not only regarding migraine prophylaxis but regarding the afore mentioned symptoms associated with PCOS. Therefore we recommend adding to any proposed regimen, ingredients like chromium picolinate, or other insulin sensitizing ingredients, plus additional dietary fiber to prevent spiking of blood glucose levels that can often lead to the precipitous drops associated with hypoglycemia.

We at MigreLief have created a safe, gentle and natural medicine for adolescent and adult women suffering from both/either menstrual/hormonally related migraines and monthly symptoms of PMS, it is called MigreLief+M. It will be available in 1-2 months. We will announce it’s availability on our Twitter, Face book and MigreLief blog sites.

>To your good health,

Curt Hendrix M.S. C.C.N. C.N.S.
Chief Science Officer, Akeso Health Sciences L.L.C.

FDA Warning: Anti-Depressants and Migraine Prescription Drugs

FDA Warns on Mixing Antidepressants with Migraine Drugs (First released in 2010)

ROCKVILLE, Md., July 20 — Mixing common migraine drugs with antidepressants can trigger a life-threatening condition called serotonin-syndrome, the FDA has warned.

Serotonin-syndrome is characterized by rapid heart beat, sudden changes in blood pressure, and increased body temperature. Other symptoms include restlessness, hallucinations, loss of coordination, overactive reflexes, nausea, vomiting, and diarrhea.

Options successful at preventing the occurrence of migraines would decrease the risk described above in patients taking anti-depressant and experiencing migraines.  

For warning signs of serotonin syndrome and more info on Anti-depressants and migraine drugs click on the link at the end of this article.  For information on your natural migraine control option recommended by doctors, neurologists and pharmacists, go to

MigreLief is a dietary supplement for the nutritional support of cerebrovascular function in migraine sufferers age 2 years and above.



Can MigreLief Help Cluster Headaches?

We are often asked if MigreLief can also help with persistent, recurrent headaches in a temporal pattern such as Cluster Headeaches.   People with migraines often misdiagnose themselves with cluster headaches and many physicians tell their patients they have migraine/cluster headaches due to overlapping symptoms.

Intractable temporal headaches or Clusters are not as completely distinct from migraines as some would think (they are different, but there is some overlap in the disorders and treatments).

Because they respond (to varying degrees) to migraine medicines and don’t fit neatly in any box MigreLief theoretically could be a good fit.  We have had some positive feedback from CLUSTER HEADACHE SUFFERERS.

If you suffer from cluster type headaches and would like to give MigreLief a try, be sure to use it for 90 days to give it sufficient time to address the underlying nutritional deficiencies and imbalances that many migraine/headache sufferers have in common.  Positive results may occur in a much shorter time however.

Each bottle of MigreLief contains a one month supply.  There is free shipping anywhere in the world for 3 or more bottles plus a money back guarantee if you are dissatisfied for any reason after 90 days of taking MigreLief.

Curt Hendrix, M.S., C.C.N., C.N.S.


Many, many, years ago, I asked my little daughter who was 5 or 6 at the time, why she couldn’t finish her vegetables but still very much wanted her dessert.  She told me, “Poppy don’t you know that desserts go into a different stomach?”

Well, as it turns out, she wasn’t far from wrong.  No, we don’t have two different stomachs, but researchers from Italy propose that our brains do react differently to foods that we love.

We have all eaten many meals where we are completely full, maybe even stuffed, and we can’t eat another bite of the main course, but still find room to eat some tempting treat or dessert.

These researchers explored how our bodies react when aroused by irresistible treats. They suggest that regardless of how full we are, our bodies are chemically predisposed to seek gratification from foods that we love.

They studied “hedonic hunger” (hunger that comes about due to the need for gratification as opposed to caloric deficit).

The study which was published in the Journal of Clinical Endocrinology and Metabolism was small only involving 8 people, so therefore is preliminary but still very interesting and suggestive.

In the early history of man, a consistent source of food was not guaranteed and depending upon hunting conditions and weather, one could go for days without eating.  So the need to overload on food when it was available, to protect against those times when it wasn’t, made sense.  This is referred to as “homeostatic” hunger. (hunger that comes about when we need to protect and sustain our basic life functions.)

That is certainly not the case, in modern times, so why do we still overeat despite the fact that we are full and usually don’t have to worry about where our next meal is coming from?  Is it possible that many of us eat “just for fun” (hedonistic hunger) and is this hunger caused by biochemical signals that are hard to resist?

The eight people studied were between the ages of 21-33. They were all healthy, not over-weight and free of any eating or dieting disorders.

The participants were fed healthy breakfasts. After an hour, they were asked how hungry they felt and were then presented with what they had previously told the researchers were their favorite food.  They were not allowed to eat the food, just see and smell it.  Later on, they were allowed to eat it.

The participants were then asked how hungry they were now, after being exposed to their favorite treat.

A month later, they went through the same test. They were fed the same breakfast. After an hour passed, the researchers asked them how hungry they were and then exposed them to a bland food combination that they were only allowed to see and smell. Later on, they were allowed to eat it.

Although the participants felt equally full after eating each of the two breakfasts, their desire, urge to eat and appetites were significantly higher after being exposed to their favorite treat as opposed to the bland food offering.

In addition, after eating their favorite food as compared to eating the bland food choice,  the blood tests of each of these people revealed, that ghrelin, a hormone made in the stomach that is a signal of hunger, jumped significantly and remained high for 2 hours, but decreased after eating the bland food option.

In other words, seeing, smelling and eventually eating the “tempting treat” actually caused significant increases in hunger that continued for 2 hours.

The take-away from this study is:  The mere presence of your favorite treats in your home can lead you to thinking about them and artificially increase your appetite and sense of hunger, even though you have previously eaten and consumed enough calories for your health and homeostatic hunger needs.

The solution is clear.


If you want to lose weight, avoid developing type II diabetes, heart disease and possibly even cancer, follow this simple advice.

Curt Hendrix M.S. C.C.N. C.N.S.

[Study] High Dose Riboflavin Can Reduce Frequency and Intensity of Migraines

Some people think of migraine headaches as being an adult health problem. Children of all ages suffer from migraine pain which can disrupt and impair their quality of life as well. According to the American Academy of Family Physicians, about 5% of elementary school-age children may experience migraine headaches and the physical and emotional stress they cause. This statistic jumps to 20 percent by the time a child reaches high school.

Before age 10, an equal number of boys and girls get migraines but after age 12 during and after puberty, migraines affect girls three times more than boys. Migraine symptoms interrupt the normal activities of 65-80% of these young migraineurs.



MIGRAINES IN MEN An article published in the 2012 March edition of the headache journal Cephalalgia, discusses a Taiwanese study that found a correlation between having erectile dysfunction (ED) and also having been diagnosed with migraines.

In over 5000 patients with ED, the odds of having also been diagnosed were 63% greater than in men without ED, and this was after adjusting for other risk factors that are associated with ED like heart disease, hypertension, diabetes, high cholesterol and alcohol abuse.

An interesting aspect of this research was that this increased risk of having been diagnosed with both migraine and ED increased from 63% to 98% in men between the ages of 30-39, an age group not usually associated with ED.

For men who suffer chronic migraines, the need to stop the pain and avoid a life of taking pain pills is enough motivation to explore options that prevent migraines. The possibility that migraines are somehow related to ED only provides another reason to explore all of the options


Curt Hendrix, M.S., C.C.N., C.N.S.

To learn more about safe, effective, non-drug migraine options please go to


In previous articles I mentioned that chronic migraine sufferers accumulate tiny lesions in their brains over time. Initially when this research came out, there was no wayof knowing if these lesions had any negative effects on brain function.

 The good news is that a second study done by researchers at the Harvard Medical School confirmed the results of the first study done in Paris, that in fact, over time the lesions did not lead to any increase in cognitive decline when comparing migraine sufferers to people without migraines.  THIS IS REALLY GOOD NEWS!

In fact, one of the several cognition tests that were used to measure cognitive decline, indicated that migraine sufferers had less cognitive decline than non-sufferers.


Curt Hendrix, M.S., C.C.N., C.N.S.


If you suffer from 1 or more migraines a week, you are a good candidate for pursuing options that prevent your migraines, instead of constantly taking pain medications after the migraine starts. To learn about a very successful option, please go to




Prescription pain killers such as Vicodin (hydrocodone) OxyContin (oxycodone), Opana (oxymorphone) and methadone can cause significant rebound headaches in chronic migraineurs who use these drugs.

The over-use of these drugs is alarming. There were enough prescriptions written for these drugs in 2010 to medicate every adult in America, around the clock for a month. The drug companies are laughing all the way to the bank.

In 1999, 4000 deaths due to these drugs were reported. Just 9 years later that number increased more than 350% to 15,000.

We are the most medicated country in the world, yet our life expectancy is not even in the top 40 countries of the world.  Our medical insurance costs are the highest in the world, but we are nowhere near the healthiest people in the world.

Now additional studies are showing that triptan drugs like Imitrex, Zomig, Frova, Maxalt and Relpax, which are used to try to reduce the pain of migraines, are dangerous for people with heart disease.  The drugs constrict arteries which is a dangerous mechanism for people with heart problems.

Yet the study reports that physicians are prescribing these drugs to people with heart problems who shouldn’t be taking them. In fact the study reported that 22% of people with heart conditions were prescribed a triptan during one year.

A well-known headache physician, Stewart Tepper of the Cleveland Clinic reporting for WebMD states, “That figure is very upsetting, I never would have thought it was that high.”

Add this concern to the fact that if over-used, these drugs cause additional migraines to occur as rebound headaches due to medication over-use, and it becomes clear that getting off of these drugs and preventing migraines from happening in the first place, should be the goal of all chronic migraine sufferers.

Go to  to start on your drug free pathway to finally controlling your migraines.


Curt Hendrix, M.S., C.C.N., C.N.S.



Dr. Marc Siegel and Dr. David Samadi weighed in on Fox News Live this morning regarding a recent study that supports a connection between migraines and depression.  He stated, “90% of all headaches we have are migraines. It’s a very good study but we don’t know if it’s the fact that you have migraines that make you depressed… maybe your lifestyle changes, maybe it’s intractable, because you are so bothered by the headaches.  Or is there something that the migraine does to the brain that alters it and makes it more prone to depression?”

“It’s 80% more likely you’re going to get depressed if you have a migraine.  So the message for people out there is be on the lookout for depression if you get migraines,” Dr. Siegel concluded.

Dr. Samadi stated it was just an observational study, not cause and effect, nevertheless useful information.  “If you get migraines, talk to your physician because there could be signs and symptoms of hidden depression.”  The doctor can then discover the depression and treat both the depression and the migraines with medication at the same time he suggested.

Two things should be noted about this morning’s news cast commentary.

First of all 90% of all headaches are not migraines.  There are two types of headaches, primary and secondary.  90% of all headaches are known to be “Primary Headaches,” whose subcategories include tension-type headaches, cluster headaches and migraines, tension –type being the most common.

Primary headaches are merely headaches that are not caused by underlying medical conditions while secondary headaches are the end result of some other medical condition such as inflammatory headaches due to a brain tumor, infection, or trauma.

Secondly, I wanted to suggest that any migraine sufferers considering prescription drug treatment for both their migraines and depression should be aware of a possible danger known as “Seratonin Syndrome” which I’ll explain at the end of this article.

The study referred to by Fox News was a recent Canadian study that concluded that people who get painful migraine headaches may be at a higher risk for developing clinical depression.

According to Reuters Health, Dr. Peter Goadsby, professor of neurology and director of the Headache Center at the University of California, San Francisco, said research linking depression and migraine headaches goes back several decades. He called the study a “useful contribution” to existing research.

Geeta Modgill, lead author of the study and her group gathered data from the Canadian National Population Health Survey, which profiled over 15,000 people and followed up with them every two years between 1994 and 2007.

Overall, about 15 percent of the people in the study experienced depression and about 12 percent experienced migraines throughout the 12 years of the study.

Cases of depression were significantly more common among people who had migraines at the beginning of the study – 22 percent of migraine sufferers got depressed, versus 14.6 percent of those who didn’t have migraines.

That made participants with migraines 80 percent more likely than people without the headaches to develop depression, and the link held up after adjusting for other influences like age and sex.

People with depression were also 40 percent more likely to develop migraines than the non-depressed.  The association disappeared when the data were adjusted for stress and childhood trauma, however.

The study also cannot determine cause and effect for the link seen between depression and migraine.

The research, published in the journal Headache, also implies that the relationship may go both ways, and people with clinical depression could have a higher risk of developing migraines.  The researchers conclude that the finding could have been due to chance.

Despite no evident mechanism, Modgill said, “Something is going on here.”

Migraine and depression sufferers should know the signs of both ailments since each might be at a higher risk for the other condition.


The frequency and intensity of migraines can vary among sufferers but commonly is characterized by

  • a throbbing headache often localized to one side of the head.
  • intense head pain usually gradual in onset, then progressively more painful.
  • sometimes accompanied by a pronounced sensitivity to light and sound or nausea and vomiting.
  • a dull, deep and steady pain or throbbing and pulsating if severe
  • can occur any time of the day, through it often starts in the morning.
  • pain in the temples or behind one eye or ear, although any part of the head can be involved.
  • may be accompanied by a variety of sensory warning signs or symptoms, such as flashes of light, blind spots, temporary loss of vision or tingling in your hand or face (MIGRAINE WITH AURA)
  • pain lasting a few hours or up to one or two days,
  • occurrence varies – once or twice a week, or only once or twice a year.



According to the DSM-IV, a manual used to diagnose mental disorders, depression occurs when you have at least five of the following nine symptoms at the same time:

  • a depressed mood during most of the day, particularly in the morning
  • fatigue or loss of energy almost every day
  • feelings of worthlessness or guilt almost every day
  • impaired concentration, indecisiveness
  • insomnia or hypersomnia (excessive sleeping) almost every day
  • markedly diminished interest or pleasure in almost all activities nearly every day
  • recurring thoughts of death or suicide (not just fearing death)
  • a sense of restlessness — known as psychomotor agitation — or being slowed down – retardation
  • significant weight-loss or gain (a change of more than 5% of body weight in a month)


Because of the migraine-depression connection, I wanted to bring up a topic I covered in an earlier MigreLief Blog Post – the danger migraineurs face when attempting to treat both depression and migraine headaches at the same time with prescription drugs.


Migraine sufferers should be aware of the dangers of combining some anti-depressants with prescription migraine medications.  Unfortunately, the mechanism of action of many antidepressants is to increase serotonin (a feel good neurotransmitter) levels in the brain. Triptan drugs like Imitrex, which are used to reduce or end the pain of a migraine attack also work by stimulating serotonin receptors.

This combination of antidepressants and triptan migraine drugs, can lead to too much serotonin in the brain. This is not a good thing and can result in a potentially life-threatening condition known as “serotonin syndrome.”

In some people, just the use of triptans drugs such as Imitrex or Zomig alone can result in unhealthy levels of serotonin, leading to serotonin syndrome. This risk increases substantially if these people are also taking an antidepressant like Pristiq or any other of several antidepressants known either as SSRI (selective serotonin reuptake inhibitors) or SNRI (serotonin-noradrenaline reuptake inhibitors).

The symptoms of “Serotonin Syndrome” are:

Rapid heart rate and high blood pressure
Agitation or restlessness
Dilated pupils
Loss of muscle control or twitching muscles
Heavy sweating
Goose bumps

In severe cases of serotonin syndrome life-threatening symptoms can occur:

High Fever
Irregular heart beat

If you and your physician decide to use this combination of drugs, you must be monitored very closely for any of these signs and symptoms of serotonin syndrome.

If your migraines are bad enough, your physician may decide to stop the antidepressant so that you can use the triptan drugs with less risk (though as mentioned above, they alone, in some users can cause serotonin syndrome).

A win-win solution for many migraine sufferers who are also suffering with depression is to consider the nutritional migraine supplement, MigreLief.  There is no additional risk of Serotonin Syndrome when using MigreLief.

To the Best of Health

Curt Hendrix, M.S., C.C.N., C.N.S.




Better Sleep Patterns Can Decrease Migraine Frequency and Intensity

A study done at the University of North Carolina by sleep specialist, Dr. Anne Calhoun found that by improving sleeping habits, women decreased their headache frequency by 29% and the intensity of the migraines they did get, by 40%.

When the number of migraine days per month is under 15, the patient is diagnosed with episodic migraine.  If 15 or more per month, the patient is considered to have chronic migraines.

The women in this study originally had episodic migraines that over a course of years converted to chronic migraines.  (This is called transformed migraine.  i.e. transformed from episodic to chronic).

It is believed that transformed migraines can come about due to multiple factors like: poor sleep habits and/or pain killing medication over-use.

86% of the women in the study reported non-restorative sleep.  In simple terms this means they still felt tired when they awoke in the morning. 80% of them watched TV or read in bed.  70% awakened between 1-6 times a night to urinate.

The women were instructed to:

  • Move dinnertime to 4 hours before bed time
  • Limit fluids taken 2 hours before bedtime
  • Allow for 8 hours a night of sleep and not to vary their bedtimes more than 30 minutes
  • Not to listen to music, read, or watch TV in bed
  • Not to over-use migraine medications
  • Stop taking naps (even though they were tired from poor sleep)

Improvements in migraine frequency happened rather quickly after implementing the “better” sleeping habits.  Within a month and a half, 35% of the group reported fewer migraines.

By the end of 3 months 58% of the women who implemented the recommended sleep changes went back to being only episodic sufferers.

The good news is that these recommendations work and that all except one of the women who implemented ALL of the recommendations reverted to being episodic from chronic.

The bad news is that women kept three or more of the bad sleep habits they didn’t improve.

So discipline is important.  Implement all of the recommended sleep changes, they are really not that hard.

What may also prove to be very exciting is to implement these sleep habit changes and combine them with doing 3-4 days a week of moderate exercise (i.e. brisk walking, moderate weight-resistance with dumb bells). Recent studies have shown that moderate exercise 3-4 days a week can prevent migraines as well as a prescription medication.

Do both of the above and don’t forget to take your MigreLief ( ) and your migraines may very well be a thing of the past.


Curt Hendrix, M.S., C.C.N., C.N.S