Welcome to MigreLief’s Official Blog for the Prevention of Migraines

September 11th, 2010


MIGRELIEF U.S. Patent #6,068,999 & U.S. Patent # 6,500,450 B1
CREATOR: Curt Hendrix M.S., C.C.N., C.N.S.

MigreLief (formerly Migra-Health & Migra-Lieve) is a popular all-natural dietary supplement for the prevention of migraines. Formulated and patented by Scientist-Curt Hendrix M.S., MigreLief is an advanced herbal formula often referred to as the “Triple Therapy” for migraine prevention. The triple therapy refers to the 3 main ingredients:

MigreLief contains high doses of:

Magnesium citrate and oxide
Riboflavin (Vitamin B2)
Puracol™ Feverfew (proprietary extract + whole leaf)

Read more…

In addition to high dose Riboflavin, a specific combination of two forms of Magnesium which maximize absorption and efficacy are used in MigreLief.

Puracol represents proprietary Feverfew science specific to MigreLief as well. While extracts of Feverfew can maximize certain phytochemicals found in the plant, like parthenolides, the extraction process can also remove other naturally occurring phytochemicals that may be required for maximum efficacy. The Puracol technology corrects this problem by simultaneously maximizing parthenolide levels while maintaiing the full spectrum of all the other naturally occurring compounds found in the whole plant.

Research studies show that almost half of all migraine sufferers have low blood levels of Magnesium – which is critical in controlling vasospasms (the contraction and dilation of blood vessels in the brain which occurs during migraines). Migraine sufferers also suffer mitochondrial energy deficiencies, which Riboflavin (Vitamin B2) can improve when given in high dosages. And the plant material Feverfew has been shown to reduce platelet aggregation, which can lead to vasoconstriction. So all 3 ingredients have been recommended for years by many doctors and top headache specialists based on the clinical studies behind them.

Because MigreLief combines all 3 of these ingredients into one formula (at the dosages double blind clinical studies show are beneficial), this herbal formula is being adopted more and more by physicians and headache clinics involved in treating migraines worldwide.

MigreLief – More Information: (Magnesium, Riboflavin, Purocal-Feverfew)

Magnesium is a nutritional supplement with numerous effects that support cerebrovascular tone. These include: 1) inhibition of platelet aggregation;2) interference with synthesis, release, and action of inflammatory mediators;3) direct alterations of cerebrovascular tone; 4) inhibition of vasospasm; and 5) stabilization of cell membranes. Some migraine sufferers with poor cerebrovascular tone have been found to have low brain levels of magnesium. Recommended daily dosages of magnesium typically range from 200 to 600 mg to compensate for this deficiency — far above what’s found in most multi-vitamins.

Riboflavin (vitamin B-2) is a precursor of flavin adenine dinucleotide(FAD). This coenzyme is an important component of the electron-transport chain. A deficiency of mitrochondrial energy reserves has been observed in some persons exhibiting poor cerebrovascular tone. This defect may theoretically be corrected by a compound such as riboflavin that improves the activity of the electron-transport chain. MigreLief provides 400mg of Riboflavin — significantly higher than most multi-vitamins or B-complex products.

Commonly recommended for its ability to support cerebrovascular tone, feverfew (Tanacetum parthenium) is rich in compounds known as sesquiterpene lactones. One of the more important of these compounds may be parthenolide, which represents 85% of the sesquiterpene lactone content in feverfew. Some scientific studies indicate that while parthenolide may be important there may very well be other phytochemicals in feverfew that are as of yet unidentified and play a role in its effectiveness. Some studies of extracts of feverfew containing parthenolide yielded no significant benefits. This led researchers to believe that certain of the unidentified phytochemicals may have been left behind during the extraction process. The ideal solution would be a non extracted feverfew product that naturally contained high levels of parthenolide and kept all of the other naturally occurring phytochemicals as well. Thus Puracol Feverfew, AKESO HEALTH SCIENCE’S proprietary non extracted plant source for feverfew with high levels of naturally occurring parthenolide was developed. Puracol Feverfew, is just one of the reasons for the superior efficacy of MigreLief which delivers optimal dosages of parthenolide. Scientific studies have found parthenolide inhibits platelet aggregation and the release of serotonin from platelets and polymorphonuclear leukocyte granules.* It has also been shown to inhibit pro-inflammatory prostaglandin synthesis and the release of arachadonic acid. Each of these phenomena are associated with migraines.* European studies have shown the benefits of feverfew on long-term cerebrovasular tone.

Two tablets provide:
Puracol Feverfew(Tanacetum parthenium) – 100 mg.
Magnesium (Citrate/Oxide 1:1) – 360mg, which is 90% of U.S. RDA*
Riboflavin (Vitamin B2) – 400 mg, which is 23,525% of U.S. RDA**Percentage of U.S. recommended daily allowance 

Contains no yeast, milk, corn, wheat, gluten, soy, sodium, salt, sugar, flavorings, preservatives, artificial colors. This product is not intended to diagnose, treat, cure or prevent any disease.