Migraine Science | MIGRELIEF

Migraine Science Category

Ocular Migraine vs. Visual Migraine — What is the Difference?

August 20th, 2019

Not all migraine sufferers experience the head pain commonly associated with migraine attacks. Some people experience a type of silent migraine with visual disturbance but no head pain. “Ocular migraine” also known as “retinal migraine” is often confused with “visual migraine” which is a symptom of visual changes or vision loss resulting from the aura phase of the common migraine.

However, for people who experience ocular migraines the visual changes are a little different and can be very frightening as they most often include temporary vision loss that can last up to an hour. Both ocular migraines and visual migraines can occur with or without a headache.

Ocular Migraine vs. Visual Migraine

Ocular or retinal migraines happen in the eye, so only affect the vision in that eye, while visual migraines occur in the brain, so affect the vision in both eyes together.

Visual Migraine or Migraine with Aura

  • · A typical migraine accompanied by aura (a variety of visual sensations like a kaleidoscope, zig zag lines and blind spots that often warn that the pain is on the way)
  • · Visual disturbances usually affect both eyes
  • · Aura usually occurs before the migraine head pain attack
  • · Condition isn’t serious but can make it difficult to function and complete tasks


Ocular or Retinal Migraine (sometimes referred to as eye migraine or ophthalmic migraine)

  • · Typically occur in one eye and affects vision when a blood vessel in the eye spasms, resulting in a lack of blood flow.
  • · Typically include a flickering blind spot or black spot near the center of your field of vision which gradually gets bigger causing vision loss
  • · Vision loss typically lasts 30 minutes (range is 10 min to 1 hour)
  • · Usually not accompanied by a headache

Temporary Vision Loss

People experiencing ocular/retinal migraines will see a pattern of black spots called “scotomas.” These black spots gradually get bigger and cause complete loss of vision. Other people will partially lose vision in one eye. This is usually characterized by blurry, dim vision or twinkling lights called “scintillations.” Vision loss is temporary and restores in under an hour.

What causes ocular/retinal migraines? Ocular migraines occur when the blood vessels to the eyes start to constrict, or narrow. This reduces the blood flow to one of your eyes. When the migraine ends, the blood vessels relax and open up, allowing blood flow to resume and vision is restored.

Ocular migraines are believed to have the same causes or triggers as regular migraines. These triggers may include:

  • Migraine Triggers· Lack of Sleep
  • · Stress or hypertension
  • · Perfumes and strong odors
  • · Bright or flickering lights
  • · Foods containing nitrates such as hot dogs and other processed meats.
  • · Foods additives such as tyramine or MSG
  • · Caffeine
  • · Chocolate
  • · Tobacco use or cigarette smoke
  • · Artificial Sweeteners
  • · Dehydration
  • · Low blood sugar
  • · Being in higher altitudes

Migraine headaches have a genetic basis, and some studies say that up to 70 percent of migraine sufferers have a family history of migraine headaches. If one parent has a migraine, there is a 50% chance of a child having it to. If both parents have migraine, a the chance of a children also experiencing migraine increases to 75%.

According to the World Health Organization, migraine headaches appear to be triggered by activation of a mechanism deep in the brain, which releases inflammatory substances around nerves and blood vessels in the head and brain. Imaging studies have shown changes in blood flow to the brain during ocular migraines and migraine auras. But why this happens and what brings about the spontaneous resolution of ocular migraines and visual migraines remain unknown.

NOTE: Temporary vision loss caused by ocular or retinal migraines, like migraine with aura is relatively minor however, you should always check with your doctor first to be properly diagnosed and rule out other serious health issues.
DIAGNOSIS: There are no diagnostic tests to confirm retinal migraine. Diagnosis is accomplished by reviewing the patient’s personal and family medical history, studying their symptoms, and doing an examination. Retinal migraine is then diagnosed by ruling out other causes for the symptoms. With retinal migraine, it is essential that other causes of transient blindness, such as stroke of the eye (amaurosis fugax), be fully investigated and ruled out. Seeing an ophthalmologist for a full eye exam is generally required for a good look at the back of the eyes.



Keeping a migraine journal/diary to help uncover and track your migraine triggers can help you understand and avoid those triggers. Popular triggers include, lack of sleep, dehydration, changes in weather (barometric pressure), eating certain processed foods like aged cheese, MSG containing foods, bright lights from computer screens/television, stress and even strenuous exercise. Avoiding your triggers once discovered, can go long way towards migraine prevention. (FREE MIGRAINE DIARY & TRIGGER TRACKER – Click Here)

MigreLief Migraine Supplements

“SAVE 20” for 20% off MigreLief when purchased at MigreLief.com


Optimizing nutritional status through supplementation is very beneficial. The dietary supplement Migrelief, both daily and as-needed formulas, provide nutritional ingredients proven to be beneficial when it comes to maintaining healthy cerebrovascular tone and function (blood vessels in the brain) and maintaining healthy mitochondrial energy reserves (the powerhouses of brain cells).


The Science of MigreLief – Nonprescription Dietary Supplements for Adult & Pediatric Migraines

July 20th, 2017


MigreLief Original Formula should be part of your “Preventive” regimen.  It is not an “Abortive.” MigreLief was formulated to help migraineurs maintain normal cerebrovascular (blood vessels that supply the brain) tone and function by addressing the underlying nutritional deficiencies and imbalances that are common to many migraine sufferers. These deficiencies lead to many dysfunctional processes in the brain.

The Science of MigreLief - Migraine Control


MigreLief is a great option and good place to start… a vitamin, a mineral and a plant, all well known for their safety, efficacy and low side-effects to establish normal cerebrovascular function instead of a lifetime on pain killers and drugs.  Magnesium, riboflavin (B-2) and the herb feverfew are listed in the American Academy of Neurology’s Evidence Based Guidelines for Migraine Prevention.  Puracol, Akeso Health Sciences proprietary blend of two  feverfew sources (whole leaf and extract), magnesium (oxcide and citrate) and high dose riboflavin (Vitamin B-2) have independently shown to have significant benefits for chronic migraine sufferers.


Nutritional deficiencies, inflammation, and vasospasm can independently and together contribute to migraine occurrence, frequency and intensity.  The multi-patented combination of ingredients in MigreLief was formulated to address the underlying dysfunctional processes in the brain that often lead to migraines once triggered. MigreLief helps to reestablish and maintain normal cerebrovascular function by addressing the nutritional deficiencies and imbalances often associated with migraines such as:

*Excessive Platelet Aggregation resulting in blood vessel changes.

*Decrease in the brain’s cellular energy reserves.  Cells lose energy production ability when the powerhouses of the cells (the mitochondria) become dysfunctional due to nutritional deficiencies.


Migrelief – Triple Therapy Ingredients: 

Magnesium is a nutritional supplement with numerous effects that support cerebrovascular tone.

These include:

1) inhibition of platelet aggregation
2) interference with synthesis, release, and action of inflammatory mediators
3) direct alterations of cerebrovascular tone
4) inhibition of vasospasm
5) stabilization of cell membranes.

Some migraine sufferers with poor cerebrovascular tone have been found to have low brain levels of magnesium. Recommended daily dosages of magnesium typically range from 200 to 600 mg to compensate for this deficiency, far above what’s found in most multi-vitamins. Several double blind placebo controlled studies have demonstrated that oral magnesium can reduce the frequency and intensity of migraine headaches in both adults and children.

Riboflavin (vitamin B-2) is a precursor of flavin adenine dinucleotide (FAD). This coenzyme is an important component of the electron-transport chain. A deficiency of mitrochondrial energy reserves has been observed in some persons exhibiting poor cerebrovascular tone. This defect may theoretically be corrected by a compound such as riboflavin that improves the activity of the electron-transport chain.

MigreLief provides 400 mg of riboflavin. Multiple studies have demonstrated that high dose riboflavin can be beneficial to both adults and children who suffer migraines.

Puracol Feverfew
Commonly recommended for its ability to support cerebrovascular tone, feverfew (Tanacetum Parthenium) is rich in compounds known as sesquiterpene lactones. One of the more important of these compounds may be parthenolide, which represents 85% of the sesquiterpene lactone content in feverfew. Some scientific studies indicate that while parthenolide may be important there may very well be other phytochemicals in feverfew that are as of yet unidentified and play a role in its effectiveness. .

Some studies of extracts of feverfew containing parthenolide yielded no significant benefits. This led researchers to believe that certain of the unidentified phytochemicals may have been left behind during the extraction process. The ideal solution would be a non-extracted feverfew product that naturally contained high levels of parthenolide and kept all of the other naturally occurring phytochemicals as well. For this reason Puracol Feverfew, AKESO HEALTH SCIENCE’S proprietary non extracted plant source for feverfew with high levels of naturally occurring parthenolide was developed.  Scientific studies have found parthenolide inhibits platelet aggregation and the release of serotonin from platelets and polymorphonuclear leukocyte granules.* It has also been shown to inhibit pro-inflammatory prostaglandin synthesis and the release of arachadonic acid. Each of these phenomena is associated with migraines. European studies have shown the benefits of feverfew on long-term cerebrovasular tone in multiple human studies.


The World Health Organization lists migraines 19th among the world’s most debilitating and disabling diseases

Migraine is the most common neurological condition in the developed world: it is more prevalent than asthma, epilepsy and diabetes combined.  In the United States alone, 37 million people .

MigreLief is a wonderful nutritinal option for migraine sufferers and has been recommended my neurologists, headache specialists and other healthcare professionals thoughout the United States and world wide.

Magnesium, riboflavin and the herb feverfew are listed in the American Academy of Neurology’s Evidence Based Guidelines for Migraine Prophylaxis.

Curt Hendrix, M.S., C.C.N., C.N.S. and Chief Scientific Officer of Akeso Health Sciences, formulated and patented MigreLief Triple Therapy with Puracol was well received by physicians at the recent Pri-Med convention and explained the science behind the success of MigreLief to a very interested audience.

Most MigreLief fans already know that MigreLief was formulated to addresses the underlying nutritional deficiencies and imbalances that are common to many migraine sufferers. But for those newcomers lucky enough to have stumbled upon MigreLief for the first time…it is not an “abortive” to treat the pain while it is occurring. It is nutritional support and daily maintenance.

MigreLief-NOW is Akeso’s fast-acting “as-needed” formula that can be take at the first sign of discomfort.  It can be used by itself as needed or combined with MigreLief Original, Children’s MigreLief or MigreLief+M (mestrual migraines).  For additinal nutritional support, 2 MigreLief-NOW capsules can be added to the morning dose of any MigreLief daily maintenance product.



MigreLief should be your first choice for migraine therapy… not the last!
Too often sufferers opt for the more invasive, complex often side-effect prone prescription drugs, botox or other approaches to their problem. MigreLief is a more natural option (vitamin, mineral and herb), it’s inexpensive and it addresses the underlying problem (it does not just mask the symptoms or temporarily ease the pain). To get started, select one of the daily formulas (MigreLief, Children’s MigreLief, or MigreLief+M for menstrual migraines), and take as recommended every day for a full 90 days to experience the benefits and evaluate how it works for you.  MigreLief-NOW is a fast-acting as-needed formula which is ideal to have on hand for those tough days when you need extra help.


100% MONEY BACK GUARANTEE – Try MigreLief Risk Free   

We’re so confident that MigreLief will make a difference, if anyone is dissatisfied for any reason, we offer a 100% money back guarantee of the product purchase price for new customers trying MigreLief for 90 days (each bottle is a one month supply).  Although many consumer/patients experience beneficial results in as little as 3 weeks, it is recommended that it be taken for the full 3 months to build blood levels for maximum effectiveness.

MigreLief can be safely combined with prescription migraines or OTC medications.  It has been known to lessen the side-effects of certain prescription drugs for many users. You may discover while taking MigreLief that you’ve effectively weaned yourself off of other migraine meds as you reach for them less and less.


Track your MigreLief progress with our Migraine Diary and Trigger Tracker.

MigreLief.com – Product Information

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MIGRELIEF COUPON CODES for a Discount on Your Next Purchase of Migraine Supplements at MigreLief.com

June 1st, 2016


Neurologist Recommended – Nutritional Support for Migraine Sufferers

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The MigreLief Migraine Regimen:
ACTION STEP 1:  Take one of 3 daily maintenance formulas (MigreLief Original, Children’s MigreLief (age 2-11) or menstrual migraine formula MigreLief+M… EVERY DAY.

ACTION STEP 2:  Keep MigreLief-NOW on hand at all times and take “as-needed” for fast acting nutritional support and neurological comfort.    (Congratulations MigreLief-NOW for winning the Amazing Wellness Award – Best Herbal Supplement of 2018.)

Migrelief 4 formulas

Why MigreLief should be your first choice for migraines

  • No prescription necessary
  • “Triple Therapy” ingredients all in one supplement (Magnesium, Riboflavin (B-2) and Puracol Feverfew)
  • No prescription necessary
  • No harmful side-effects
  • No caffeine – no aspirin – no ibuprofen – no acetaminopohen – no naproxen.
  • No butterbur
  • Satisfaction guaranteed or your money back after trying MigreLief for the first time for 90 days
  • Does not cause rebound headaches (medication overuse headaches)
  • Magnesium, Riboflavin and Feverfew are listed in the ‘The American Academy of Neurology’s Guidelines for Migraine ProphylaxisMenstrual Migraine Sufferers… Try MigreLief+M.  +M has the same triple therapy ingredients as Original MigreLief PLUS 5 additional ingredients to modulate blood sugar and hormone fluctuations which are well known migraine triggers.



HEADACHE clinics recommend Rev May 2013

What Healthcare Professionals are Saying About MigreLief…

~ We have multiple patients on MigreLief & have had positive benefits.  There are many patients who want to go the route of non-prescription supplements and MigreLief is the answer.”  
– Marian F., NP – Morton Neuroscience Center, Clearwater, Florida

~ “I run a headache clinic and suggest your products frequently. Thank you.”
– Brian R. MD. – Cooks Children’s Neurology  (More Reviews)


MigreLief has been recommended by neurologists and headache specialists for 2 decades.
3 mechanisms of action make MigreLief a great option for migraine sufferers.  Puracol™ Feverfew, a proprietary blend of two unique feverfew sources, magnesium from two sources and high dose, highly absorbable riboflavin (Vitamin B-2) have independently shown to be of significant  benefit to chronic migraine sufferers.  Ingredients- details

Nutritional deficiencies, inflammation, and vasospasms can independently and together contribute to migraine occurrence, frequency and intensity.

The Science of MigreLief Migraine PreventionUnderstand THE SCIENCE OF MIGRELIEF.


If you are battling recurring migraines also known as “REBOUND HEADACHES” click on this link to understand why your headaches keep coming back and how you can stop the vicious cycle of MOH headaches.

Redeem your coupon at MIGRELIEF’S OFFICIAL WEBSITE  MigreLief.com


MigreLief Original Formula

Children’s MigreLief (age 2-11 or under 100 lbs) – safe, gentle and effective

MigreLief+M Menstrual/Hormonal Formula– (5 dditional ingredients added to address hormone and blood sugar fluctuations)

MigreLief-NOW – Fast Acting comfort formula to be taken as needed.