Migraine Drugs | MIGRELIEF

Migraine Drugs Category

Hair Loss from Topamax? Recommendations for Battling Topirimate Side-Effects

December 25th, 2017

Topamax and Hair Loss

hairloss from topamax
Topical Treatments and Nutritional Options

Discover What’s Working for Others

If you search online for “Topamax and Hair Loss” you will find many posts from people struggling with this problem and seeking advice. Just why and how Topamax causes hair loss for some users is not known, but more and more users are reporting this side-effect.

The NIH (U.S. National Institutes of Health) list hair loss as a side-effect of Topamax.  Topiramate is an anti-seizure drug taken to help prevent migraines. It can cause mild-moderate to serious side effects that may include abnormal sensations (often tingling), fatigue, nausea, changes in taste, loss of appetite, diarrhea, and weight loss. More severe side effects can occur, including difficulty with thinking and concentration.

Topiramate -additional side effects. (see bottom of page for MedlinePlus list.)

Topiramate may cause osteoporosis (a condition in which bones can break more easily) in adults and rickets (abnormal, curved bone growth) in children. Topiramate may also slow the growth of children and may decrease the final height that children reach. Talk to your doctor about the risks of taking topiramate.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Two Tactics for Combating Hair Loss:

From the inside (nutritionally) and from the outside (topical treatments)

Topical Treatments:
Some people have had success with the following products when applied to hair and scalp

Nioxin shampoo and products for thinning hair – Often recommended for cancer patients who lose their hair due to chemotherapy, Nioxin can be found in many retail stores, beauty supply stores and online.

Ginger Ginger Root & Coconut Oil for Stimulating Hair Regrowth – Purchase fresh ginger root from the produce department of your grocery store and a jar of coconut oil.  It will be solid but easily melts at ward temperatures or when heated.

Preparation:  Peel and slice ginger into small pieces to fit in a blender or food processor.  Blend to a pulp (do not add water) and then place the ball of pulp on a thick towel, wrap and squeeze the juice into a bowl.  Melt the coconut oil by placing it in a small bowl and then placing the bottom of the small bowl into a larger bowl filled with hot water.  Never microwave the oil or it will destroy the beneficial properties.  Add the squeezed ginger juice to the coconut oil and mix with a spoon.  You may put this concoction in a plastic or glass jar, bowl or bottle for storage. Glass is best as you can place it in warm/hot water to melt each time you want to use it.   If you store it in a bottle with a dropper it is easy to apply with the dropper to you scalp.

May purchase at Whole Foods Market or other stores.

You can also use a small paint brush or drizzle it on with your fingers.  Massage into your scalp.  You can tie up your hair or pin it back while the mixture stays on your scalp for  at least 2 hours before washing it off with cold water.  Shampoo and condition as normal.    You may also use it before bedtime, put a plastic shower cap on your head or lay your head on a towel when you sleep due to the slight oiliness.  You can wash out in the morning with your regular shampoo.  The great properties of ginger and coconut oil will nourish your hair, prevent breakage and stimulate hair growth. Use it regularly at least 3 times a week if  you have hair loss problems and don’t just want to stimulate your hair follicles, prevent dandruff and keep your hair nourished.  Here is a great online video with step by step instructions.  Ginger Root Coconut Oil Treatment Video.

Rosemary Oil (herb) – Although it’s not clear how rosemary works for hair loss, applying it to the scalp irritates the skin and increases blood circulation.  Using rosemary oil for hair loss is one of the most effective, natural solutions. Rosemary essential oil stimulates circulation to the scalp and destroys any bacteria that could clog hair follicles.

Rosemary for Daily Use – You may also use rosemary oil for hair loss on a daily basis through scalp massage and with daily shampooing. For a daily massage to stimulate new growth, add two drops of rosemary oil to one ounce of jojoba oil. Rub into the scalp for three minutes in the morning before showering. Another tip for nourishing your hair on a daily basis is to add rosemary to your shampoo or conditioner. Use one drop of oil for every four ounces of shampoo or conditioner. For hair loss, rosemary essential oil blends well with lavender, sage or peppermint. If blending, use half rosemary essential oil and half of your choice of another oil.

Hot Oil Hair Treatment – Once a week use a hot oil treatment for your hair and scalp. Combine 5 drops of rosemary essential oil with 3 tablespoons of extra virgin olive oil in a small jar with a lid.  Warm the oil-rosemary solution by placing the jar in a bowl of  hot water (recently boiled) the oil is warm.  Comb through damp hair. Wrap a bath towel around your head to keep in the heat and let stand for 20 minutes or more.  The rosemary treatment and heat will increase circulation to the scalp and you should see an improvement with hair growth

Lavender & Other Essential Oils for Hair Growth –  This is a treatment that has been recommended for people with Alopecia areata (a type of hair loss that occurs when your immune system mistakenly attacks hair follicles, which is where hair growth begins).  This essential oil blend includes lavender, thyme, rosemary, cedarwood, plus the carrier oils jojoba and grape-seed (a carrier oil dilutes the essential oils and aids in the delivery of their healing properties without irritation).
To make an essential oil blend, mix the following:
3 drops of lavender oil
3 drops of rosemary oil
2 drops of thyme oil
2 drops of cedarwood oil
4 tsp. of grapeseed oil
1/2 tsp of jojoba oil
Mix the oils well before massaging the oil into your scalp. Apply to a small patch of your scalp before putting it on your entire scalp, to see how your skin reacts. If you do not have a negative reaction, massage the mixture into your scalp five minutes, being sure to cover bald or thinning spots. If the lavender oil becomes overwhelming to your senses, add a little more of one of the carrier oils (grapeseed, jojoba or even olive oil) to further dilute the mixture. Try not to dilute the oil too much, though, because you may lose the benefit. After you’re done, cover your hair with a towel. It’s suggested, that to see the best results, one should do this routinely for at least seven months. Apply before bed, and wash your hair in the morning.

Nutritional Options: Many people experience improvement (with hair loss AND migraines) when they address nutritional deficiencies

Biotin – is a member of the B-vitamin family known as Vitamin B7 and helps with cell growth and blood sugar maintenance. It has been proven to help hair grow stronger and longer and it also helps strengthen your nails.h It has even been shown to reverse premature graying.  It is especially important to the skin cells as they are frequently replaced due to their exposure to the outside environment. Biotin also protects the nervous system, preventing seizures, ataxia and loss of muscle tone.

Biotin is also great for stress because it’s an important component of the nerves. Stress can cause hair loss so adding biotin to the diet gives protection both to the hair follicles and to the nerves that support their proper function.Check the supplement bottle for recommended dosage.  Many people start with 1,000 mcg. for hair loss  with a possibility of increasing up to 5,000 if they are not experiencing success at a lower dose.

Topamax and MigreLief  MigreLief 4 formulas

We often receive emails from patients informing us that MigreLief was recommended to them in combination with Topamax.  Although we have no knowledge of MigreLief helping with hair loss specifically, MigreLief has been reported to work well with Topamax in the reduction of side-effects in some users.

MigreLief contains Magnesium, high dose Riboflavin and the herb Feverfew (a proprietary form of whole leaf and extract.)  MigreLief was formulated to address the underlying nutritional deficiencies and imbalances, as well as dysfunctional brain processes, that lead to migraines in the first place.

MigreLief works by helping a migraine sufferer to maintain the normal cerebrovascular tone and function he or she enjoys on migraine-free days.  If you add MigreLief to your migraine prevention regimen, we suggest taking it for 90 days for maximum benefits.   Although many migraine sufferers have reported success in less time, the 90 days is sufficient time to build up nutritional levels for maximum effectiveness.  During this period, fast acting MigreLief-NOW may be kept on hand at all times and taken at the first sign of discomfort.

MigreLief – 4 Formulas to Meet Everyone’s Needs

Available in 3 daily maintenance formulas:  Original, Menstrual Migraine and Children’s (age 2-11)
Fast-Acting “As-Needed” formula:  MigreLief-NOW – taken at first sign of discomfort

migrelief migraine prevention natural relief


In addition to medications, the following can also lead to hair loss:

  • Hormonal changes, including menopause
  • Increased production of DHT, a form of testosterone
  • Stress
  • Alopecia, or pattern baldness
  • Nutrient deficiencies
  • Thyroid issues, especially in regards to an iodine deficiency
  • Illness and medication

For hair loss in general, maintaining a healthy lifestyle will promote hair growth.  Eating a healthy diet and getting plenty of sleep to regenerate cells and promote overall health is very important.  Foods rich in iron, vitamin A & D are known for supporting healthy hair;  spinach, bok-choy, carrots, sweet-potatoes, nuts, fish, chicken, and blueberries, to name a few, all will contribute to healthier hair. Taking MigreLief, drinking plenty of water, eating a healthy diet rich in vitamins and minerals  while avoiding stress and other well known migraine triggers when possible, will all contribute to a migraine preventive regimen better quality of life.

Follow the links below to additional online  forums discussing hair loss and Topamax.  Visit MigreLief.com for more information.


Topamax and hair loss suggestions? – MDJunction

  • www.mdjunction.com/forums/migraine-headaches-discussions/general-support/10… I have been on 75mg of topamax for the past 8 months. I lost around 12 lbs. but I’ ve noticed that my hair has been falling out.  I take many 
  • Can Topamax Cause Alopecia?  – 2015 study
  • So sad to stop Topamax, but can’t deal with hair loss – Topix

    www.topix.com/forum/drug/topamax/TFRFH8A8NCDNCVMN2 – Similar to So sad to stop Topamax, but can’t deal with hair loss – Topix I’ve had every test there is and still have no diagnosis (possible MS? freak migraines?), but my neuro put me on Topamax. It was awesome.

  • Hair loss and Topamax – Weight Loss Alternatives – MedHelp

    www.medhelp.org/posts/Weight-Loss-Alternatives/Hair-loss-and-To… – Similar to Hair loss and Topamax – Weight Loss Alternatives – MedHelp Sep 4, 2006  I have been prescribed Wellbutrin for depression and Topamax as a mood stabilizer. The combination worked very well for me and the bonus 

Is “Hair Loss” Even Listed as a Side Effect?!

It’s always good to read the warnings regarding side-effects before starting a new drug. However, many people have stated that hair-loss is not listed as a side-effect of Topamax.  It doesn’t appear that hair loss is mentioned anywhere, confirming the frustration of so many migraine sufferers – they didn’t expect it, making it all the more aggravating.  But if you take a closer look – the hair loss information may be there, but in disguise, referred to as Alopecia.

According to the official Topamax website, the common side-effects are numbness and tingling in the arms and legs, fatigue, taste change (food and drink tastes different), difficulty with concentration and difficulty with memory.  Hair loss is not mentioned.  Serious Topamax side-effects are described in the manufacturers Important Safety Information section.

MedlinePlus, an informative drug database and service of the U.S. National Library of Medicine and National Institutes of Health provides a lot of information, but does not seem to mention anything about hair loss.

Topamax and Hair Loss – What Can You Do?

Visiting online forums is a good way to read the stories of others who are experiencing the same dilemma and discover what is or isn’t working.  Nutritional options and remedies are also shared. You’ll see that users share their frustration about their hair loss from Topamax, and about being uninformed of this side-effect …with a few people stating it could take a year for hair to grow back once stopping Topamax. However, there are many who are experiencing regrowth as they supplement their nutritional deficiencies, and others who benefit from the information provided in the Hair Loss Black Book, and the Women’s Hair Loss Project is also another resource.

Additional Information:
MedlinePlus (U.S. NIH National Library of Medicine) Topirimate Info & List of Side-effects

Topiramate may cause other side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • numbness, burning, or tingling in the hands or feet
  • slowed reactions
  • nervousness
  • headache
  • drowsiness
  • weakness
  • uncontrollable shaking of a part of the body
  • uncontrollable eye movements
  • weight loss
  • constipation
  • heartburn
  • change in ability to taste food
  • dry mouth
  • nosebleed
  • teary or dry eyes
  • back, muscle, leg, or bone pain
  • missed menstrual periods
  • excessive menstrual bleeding

Some side effects can be serious. If you experience any of the following symptoms or those listed in the SPECIAL PRECAUTIONS section, call your doctor immediately:

  • blurred vision
  • loss of vision
  • double vision
  • eye pain
  • eye redness
  • worsening of seizures
  • feeling cold, chills, or low body temperature
  • difficulty concentrating
  • speech problems, especially difficulty thinking of specific words
  • confusion
  • memory problems
  • loss of coordination
  • pounding or irregular heartbeat
  • chest pain
  • shortness of breath
  • trouble breathing
  • fast, shallow breathing
  • inability to respond to things around you
  • excessive tiredness
  • diarrhea
  • nausea
  • vomiting
  • stomach pain
  • loss of appetite
  • intense back or side pain
  • bloody, cloudy, or foul-smelling urine
  • constant need to urinate
  • difficulty urinating or pain when urinating
  • fever or other signs of infection

Topiramate may cause osteoporosis (a condition in which bones can break more easily) in adults and rickets (abnormal, curved bone growth) in children. Topiramate may also slow the growth of children and may decrease the final height that children reach. Talk to your doctor about the risks of taking Topiramate.

Topiramate may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Migraine Prevention Drugs, Topiramate and Amitriptyline Prove No Better than Placebo in Children

November 12th, 2016

Alternative for Children's Migraines

Scientist and patent holder, Curt Hendrix explain the science behind the success of MigreLief migraine formulas.

Last month, Akeso Health Sciences attended annual conferences of the AAP (American Association of Pediatricians) and the CNS (Child Neurology Society) to exhibit its migraine supplements as effective nutritional support for children aged 2+ suffering either chronic or episodic migraine.

It was great to meet face to face with some of the neurologists, headache specialists and other healthcare professionals who have been recommending MigreLief supplements for years.  Both MigreLief formulas, “daily maintenance” and “fast-acting help” were well received.
It was at the recent CNS convention that we were first informed of the study regarding the use of topiramate and amitriptyline for migraine prevention in children.  The study was published simultaneously with its presentation at the annual meeting of the Child Neurology Society in Vancouver.

A randomized, double-blind, placebo-controlled trial of 328 children and adolescents aged 8-17 who were diagnosed with migraines (with our without aura) concluded that amitriptyline and topiramate proved no better than placebo at preventing migraine in children and were associated with adverse side-effects.

In the study, the participants recorded the number of headaches they experienced during a 28 day baseline period and then were given either a placebo, topiramate, or amitriptyline during a 24 week trial period.  The drug doses were increased every 2 weeks over an 8 week period with doses modified according to side-effects.  In the end, no differences in effectiveness were seen between the two drug groups and the placebo group, however, the authors observed higher rates of adverse side-effects overall in the active treatment groups than the placebo.

Amitriptyline users more often reported fatigue (30%) and dry mouth (25%), whereas topiramate users more often reported parathesia (31%) (burning or prickling sensation that is usually felt in the hands, arms, legs, or feet, but can also occur in other parts of the body), and weight loss (8%).  Other side-effects reported with topirimate included, fatigue (25%), dry mouth (18%), memory impairment (17%), aphasia (16%), cognitive disorder (16%), and upper respiratory tract infection (12%).  Serious adverse events included altered mood in three patients in the amitriptyine group and one suicide attempt in the topiramate group.

Before the trial was concluded, the Food and Drug Administration approved topiramate for the treatment of episodic migraine in adolescents aged 12-17 years.

“Given the null outcome in this trial and the adverse events and serious adverse events reported in the amitriptyline and topiramate groups, the data do not show a favorable risk-benefit profile for the use of these therapies in pediatric migraine prevention, at least over the 24-week duration of the trial,” the study authors concluded.

If you are a parent of a young migraine sufferer, consider MigreLief nutritional migraine supplements.

To the Best of Health,

Curt Hendrix, M.S., C.C.N., C.N.S.
Chief Scientific Officer
Akeso Health Sciences


Click to view original article published online Oct 27, 2016 – The New England Journal of Medicine.

Click to view Children’s MigreLief product information pdf – Children’s MigreLief and Fast-Acting MigreLief NOW (Age 2+)







Where to Buy MigreLief?

May 10th, 2015

Independent Pharmacies - MigreLief small Jpeg

Click here to use MigreLief’s Store Locator


Within the United States: MigreLief can be purchased from the manufacturer online at MigreLief.com or in many independent pharmacies.  If your pharmacist doesn’t stock MigreLief, you can ask them to order it for you. They should have it in stock within 24 to 48 hours, as most major drug/OTC pharmaceutical distributors carry MigreLief.

Are you looking for a nearby store where to buy MigreLief?  MigreLief is available in select stores, pharmacies, and doctor’s offices throughout the United States. Use MigreLief’s Store Locator to find a location near you that carries MigreLief.

Outside of the United States: To purchase MigreLief online go to: MigreLief.com or call 1-800-758-8746 to speak with a MigreLief representative. Order 3 directly from MigreLief.com and shipping is free – perfect for migraine-sufferers located outside of the United States.


Proven Track Record – Healthcare Professionals and Consumer/Patients Trust MigreLief

Effective Non-Prescription Option for Migraine Control
As a safe, nutritional approach to managing migraines, MigreLief has been the supplement of choice for chronic migraine sufferers since 1997, many of whom were introduced to MigreLief through their neurologists or other healthcare professionals.

MigreLief was formulated to address the underlying nutritional deficiencies and imbalances that can cause migraines and are common to many migraine sufferers.  As MigreLief’s popularity continues to grow, migraine sufferers are becoming increasingly aware of the need to maintain healthy and normal cerebrovascular tone and function. (“Cerebrovascular” refers to the blood vessels that supply the brain.) MigreLief’s Triple Therapy ingredients (3 mechanisms of action) help you to maintain the already normal cerebrovascular function you have on non-migraine days.  (MigreLief Ingredients)


New to the MigreLief Community?

Here is why MigreLief should be your FIRST CHOICE if you suffer chronic migraine headaches:

  • * It works!
  • * Triple Therapy ingredients are proven to lower the frequency and intensity of migraines and are listed in The American Academy of Neurology’s Guidelines for Migraine Prevention.
  • * Taken daily as you would a vitamin
  • * Multi-patented formula
  • * Addresses the underlying nutritional deficiencies and imbalances that can cause migraines
  • * Helps to maintain normal cerebrovascular tone and function
  • * No harmful side-effects
  • * Safe for men, women and children over the age of 2.
  • * Neurologists, leading headache clinics, pharmacists…recommend
  • * May be combined with other migraine medications or used by itself
  • * Created by Curt Hendrix, M.S., C.C.N., C.N.S. -Chief Science Officer of Akeso Health Sciences and Concourse Health Sciences;  Named as Principal Scientific Investigator in multiple NIH (U.S. National Institutes of Health) governmental grants studying the benefits of natural medicines on disease.


To the Best of Health,

~ The MigreLief Team

Best Migraine Treatment



Finally! A FAST-ACTING, Non-Prescription, Nutritional Option for MIGRAINE & HEADACHE Sufferers.

May 1st, 2015

MigreLief NOW Fast Acting Migraine Help

For those times when MIGRAINE and HEADACHE sufferers need help the most… NOW!

MigreLief-NOW is a FAST-ACTING, drug-free, non-prescription, safe and superior alternative to the chronic use of NSAIDS, analgesics and  anti-inflammatories.

MigreLief-NOW ingredients:  Aflapin Boswellia, Cerevasc Ginger, Puracol Feverfew & Magnesium

  • NO Aspirin
  • NO Caffeine
  • NO Acetaminophen
  • NO Ibuprofen
  • Kosher, Vegetarian, and Gluten-Free

MigreLief-NOW may be used by itself on an “AS NEEDED” basis, or combined with any of the MigreLief daily maintenance formulas used by chronic migraine sufferers (MigreLief, Children’s MigreLief or MigreLief+M).  MigreLief-NOW may also be combined with medications.

Recommended usage:  Adults take 2 to 4 capsules immediately (may take two more capsules two hours later, if needed).  Children age 2-11 may take half of the adult dose – 1 or 2 capsules immediately (one more capsule two hours later, if needed).

Reach for MigreLief-NOW instead of medications or pain-relievers. (Avoid their side-effects too!)  Possible side-effects from NSAIDs include:

  • Heart Attack
  • Stroke
  • Kidney Damage
  • Liver Damage
  • Ulcers
  • Bleeding
  • Hair Loss


Avoid negative side-effects and choose drug-free fast-acting MigreLief-NOW!


Read more about MigreLief-NOW.

Click HERE to Buy Now



April 11th, 2014

Can the pain pills you take for your headaches and migraines, menstrual pain, back aches and arthritis put you at risk for liver damage/failure, kidney damage, increased stroke risk, bleeding, ulcers, hearing loss cardio vascular risk and certain types of cancer?

The answer is a resounding “YES.”

Tens of millions of people suffer chronically from pain caused by migraine headaches, arthritis or other pain causing conditions.  Tens of millions of people take pain pills every day, every week or every month and run the risk of significant damage to their short and long term health.

Pain Pill Dangers - AcetaminophennJust recently the FDA announced that just taking the maximum allowed dose of acetaminophen for two weeks could cause significant liver damage.  It is widely known that aspirin can cause bleeding, ulcers, and many feel that unless you have already had a heart attack, the risk of taking it daily even at the baby aspirin dose of 81 mg outweighs the rewards.

Ibuprofen and Naproxen – Nevertheless, frequent NSAID use can contribute to a number of issues. Perhaps the most common medical problem arising from chronic NSAID use is gastritis, or inflammation of the lining of the stomach. NSAIDs decrease the body’s ability to create a natural protective layer between the lining of the stomach and stomach acid. Without this protection gastric acid can damage the stomach and lead to pain and inflammation. Another frequent effect of chronic heavy NSAID use is damage to the kidneys. NSAIDs can decrease blood flow to the kidneys and over time lead to loss of function. If you are using ibuprofen every day to help control headaches, paradoxically the medicine itself may actually be contributing to them through a process called medication overuse headache (rebound headache).

A study published in the journal, Circulation 2011, examined the effect of ibuprofen taken by otherwise, healthy people to treat aches and pains. An increased risk of heart related deaths was found in this group.

In an article published in the American Journal of Medicine, 2010 Mar; 123(3):231-7 it was reported that the regular use of aspirin, NSAIDs, or acetaminophen increases the risk of hearing loss in men.

In a 2011 article published in the Journal of Clinical Oncology, the researchers found that using acetaminophen four times a week or more for four years increased the risk of certain types of blood cancers by 200%.

The FDA is now requiring that prescription medicines that contain acetaminophen, must add the risk of serious skin reactions that can be severe or even fatal, to their labels.

With this in mind, do you really want to be taking any of the drugs mentioned above on an on-going basis?  Do you want to expose your children to these risks when effective and much safer options exist?

There exists substantial clinical (human) data that certain naturally occurring phytochemicals found in specific plants/spices can control and or eliminate pain and inflammation just as well as the drugs discussed above, but most importantly without any of the numerous RISKS that were disclosed in the medical literature.

To learn about which plants/spices can help you safely control your pain, please click on the following link:  

“Clearly Safer and Superior Natural Ingredients Providing Relief for Headache, Migraine, Menstrual, Muscle and Joint Pain.”


Curt Hendrix M.S.  C.C.N. C.N.S.



Cephalgiaphobia May Lead to Chronic Migraines

August 11th, 2013

Worry womanA Vicious Cycle

Cephalgiaphobia is a psychological state that has been linked to prompting and sustaining the overuse of medication.

According to a recent study, published in the Journal of Headache Pain, frequent migraines can lead to a fear of migraines, and a fear of migraines can lead to increased migraine frequency.

Depression and anxiety are common with chronic migraine sufferers.  The link between migraine and lifetime anxiety disorders (panic, obsessive-compulsive disorders, generalized anxiety, phobias) has been described in both clinical and population-based studies.

A headache or Cephalalgia is pain anywhere in the region of the head or neck.   Cephalgiaphobia is fear of having a headache, or fear of the next headache during the time you are pain free.  This fear may induce patients to use analgesic medication in the absence of pain to prevent headaches and to improve their performances.

A recent study was aimed at assessing if cephalalgiaphobia is related to migraine frequency or medication overuse, and if it can increase migraine frequency.  This term is not only used for patients that are fearful of headache pain, but also for those exhibiting pain-panic.

Pain-panic situation is described as a significant and uncontrolled fear over anticipated painful events, which can prompt excessive and obsessive drug-taking behavior and, ultimately, medication overuse (prescription or OTC pain killers). Medication overuse in turn can lead to more pain in the form of MOH or medication overuse headaches.

In a recent pilot study, moderate-high migraine frequency was associated with higher risk of cephalalgiaphobia.  Chronic migraineurs with medication overuse had a higher score of cephalalgiaphobia than those without medication overuse.  Patients with increased migraine frequency had higher cephalalgiaphobia.

The study concluded Cephalalgiaphobia may represent a high-frequency migraine feature and may play a role in chronicization. Therefore, it should be better investigated by clinicians and treated or prevented in order to reduce the risk of disability and the increase in migraine frequency.

Study details:  http://www.thejournalofheadacheandpain.com/content/14/1/49

Chronic migraine sufferers in general, including those at risk of becoming chronic are great candidates for migraine prevention.  MigreLief should be part of any chronic migraine sufferers preventive regimen.

Why MigreLief Works:

Many things can happen physiologically that can contribute to migraines occurring.

When chronic migraine sufferers get these factors under control:

  • 1- Maintain normal platelet aggregation
  • 2- Reduce or eliminate vasospasms
  • 3- Maintain normal mitochondrial energy reserves in the brain

The beneficial results can be life altering.  MigreLief addresses these factors along with the underlying nutritional deficiencies and imbalances that can cause migraines which is why MigreLief has been recommended by leading headache specialists and top headache clinics:

HEADACHE clinics recommend Rev May 2013

Prevention is KEY to controlling migraines.
When temporary relief is not an option, opt for long term relief.  If your chronic migraines are due to MOH and you are experiencing rebound headaches, it may be time to detox in order to break the vicious cycle of recurring migraines.

Learn more about MigreLief and beating medication overuse headaches 

Coupon Aug 30 2013 exp


Breaking The Cycle of Rebound Headaches Caused by Excessive Use of Prescription Drugs

August 4th, 2013

Medication Overuse Headache- (MOH) – A big dilemma.

The following comment is from Stephen Silberstein, M.D.,  director of the Jefferson Headache Center and professor of neurology, Thomas Jefferson University in Philadelphia

“One of the greatest bugaboos we see every day in headache centers is patients with chronic daily or near-daily headache, who are overusing medication. It is our most common problem. These patients have often not responded to treatment and in an attempt to treat themselves, actually make the problem worse. This is not addiction or an attempt to get ‘high’; rather, it is motivated by the patient’s desire to relieve pain and dysfunction. Migraine preventive therapy is grossly underused.”

Do you find yourself taking more and more medications to try to keep your migraines/headaches under control? Do you find that one or two days after taking your medications that your headaches return?  Do you use more than three triptan drugs a week?  Are you taking OTC drugs 15 days or more out of every month?

If your answer to any of the above questions is “YES”, then you may very well be suffering from Medication-Over-Use-Headaches.  The drugs you are taking are actually causing you to experience more headaches, even if they temporarily help the headache at hand.

Triptans, ergot drugs, opiates (morphine, codeine, meperidine (Demerol), oxycodone (Oxycontin) (Butorphanol) and OTC pain pills can all cause medication over-use headaches (MOH). If people use 3 or more triptans a week they will probably get rebounds, the same for opiates and if they are using Excedrin or other OTC pain pills 12-15 days a month or more, they will be at higher risk for rebound headaches as well.



Research has shown that withdrawing (detoxing) from these drugs can in many cases reduce the total number of headaches you experience as well as the intensity of those headaches.  Withdrawal is not easy and the symptoms of withdrawal can be challenging, but the results are definitely worth it for most sufferers.

For triptans, the detox period during which there may be withdrawal symptoms, like continuing headaches, nausea, vomiting, and disrupted sleep will last about 4-5 days on average. 

The symptoms may last up to 8-10 days for withdrawing from opiates, ergots or OTC drugs.

The literature and research states that it is important to start taking a preventive treatment product prior to or at the same time you start the detox program. (see www.MIGRELIEF.COM) We recommend starting MigreLief one week before withdrawing from the drug that is being over-used.

Keep a rescue pain medication available that is different from the medication that has been over-used, for emergency situations, only!


If withdrawing from OTC medications, keep a triptan or opiate drug available for an emergency rescue situation only. 


At the end of 5-10 days, depending upon what medication you are withdrawing from, you should find that your rebound headaches have significantly diminished or disappeared.

Your use of the offending medication should be either eliminated or substantially reduced.  Be sure to keep taking MigreLief daily because preventive products are very important to the success of this program.  Continue to take  MigreLief to maintain the benefits you have achieved.  


To the Best of Health,


Curt Hendrix, M.S., C.C.N., C.N.S.

Coupon Aug 30 2013 exp

 WARNING: The above recommendations are based upon review of some literature discussing detoxing or withdrawing from drugs causing Medication-Over-Use-Headaches. It is for education purposes only. It is not a substitute for medical advice. It is necessary to discuss your particular situation with your physician before starting on this kind of program.


Buy Now - Natural Remedy for Migraines
MigreLief – The only multi-patented, physician recommended nutritional supplement for either men, women or children over 2  years of age, who suffer from chronic migraine.




Migraine Drug Sales are Expected to Almost Double Over the Next 8 Years. One Must Ask Oneself Why?

December 3rd, 2012

Remember When a Billion Dollars Used to Be a Lot of Money?  Well It’s Not Enough for the Pharmceutical Companies. Migraine Drug Sales are Expected to Almost Double Over the Next 8 Years.  One Must Ask Oneself Why?

One of the world’s leading research and advisory firms for pharmaceutical and healthcare issues, Decision Resources, recently reported that the market for migraine therapies will increase tremendously in the next 8 years.  If all of these pharmaceutical drugs advertise how effectively they put an end to migraine pain, then why are their sales projected to almost double over the next 8 years, going from 3.3 billion to 5.8 billion by 2021.

The population is not expected to come close to doubling in this time period, so does this mean that there will be twice as many people who have migraines? Could this mean that these drugs are actually causing more migraines in the people who use them? The answer is YES!

The concept of “MOH” (medication-overuse-headaches) is well-known and written about by dozens of neurologists and headache/migraine experts in published medical journals. It basically states that using both prescription and over-the-counter drugs too often to treat migraine pain actually results in an increased number of new migraines. These additional new migraines caused by over use of these drugs are also referred to as rebound headaches.

A recent article which reported this projected increase in migraine drug sales also stated that “the largest unmet need for migraine sufferers was in the use of prophylactic options (products that prevent the migraines from occurring rather than just taking something to try to reduce the pain after a migraine has already started).

The article went on to state that no new prophylactic options are projected to be available before 2021. Fortunately, one of the best, safest, effective, non-drug options to maintaining the normal cerebrovascular function that you have on your migraine-free days, is available right now at CVS stores throughout the U.S. as wells as on CVS.com and MigreLief.com



Curt Hendrix, M.S., C.C.N., C.N.S.

MigreLief is Covered by Flexible Spending Plans (Pre-Tax Dollars)

November 23rd, 2012

As the end of the year approaches and employees enrolled in Section 125 FLEX PAY PLANS calculate the dollars left in their flexible spending account (FSA) or healthcare spending accounts (HSA) due to the “Use it or lose it” policy,  it is a good time to remember that MigreLief is considered an OTC (over the counter) item that qualifies for reimbursement under your flex-pay plan.

Pursuant to Revenue Ruling 2003-102, over-the-counter drugs that are used to alleviate or treat personal injuries or sickness are now reimbursable through health care flexible spending accounts. Employees’ flex pay pretax contributions are not subject to federal, state, or social security taxes.  In general, individuals must use funds from a flexible spending account for medical care. Medical care is for the diagnosis, cure, mitigation, treatment or prevention of disease, OR for the purpose of affecting a structure or function of the body (section 213(d) of the Internal Revenue Code).

Per the IRS  – Eligible expenses include, “Dietary supplements or herbal medicines to treat medical conditions in narrow circumstances.”

MigreLief qualifies however, as of 2011 qualifying OTC items require a note from your doctor.

Many MigreLief users have been prescribed MigreLief by a neurologist, general practioner or other healthcare professional for medical purposes. If you use MigreLief for managing your migraines, approach your healthcare practioner for a prescription to be placed on file with your flex-pay plan administrator so you can purchase it monthly with your pretax dollars.

Studies have shown that employees on average lose approximately $100 annually in forfeited balances within their employee health care flex spending accounts because any money remaining in your flexible spending account on Dec 31 disappears and is retained by your employer.

If you have money in your flex-pay account at year end, stock up on MigreLIef or other items from the list below to avoid losing those dollars.

Many other OTC items you may not have considered also qualify for reimbursement with a note from your doctor.  The following is a list of common non-prescription over-the-counter items the IRS has determined to be primarily for medical care and eligible for reimbursement, and dual purpose items that are reimbursable with a physician’s statement.

Note:  This list does not include all reimbursable items but is the best guidance provided by the Internal Revenue Service to date.


Allergy medicine




Anti-diarrhea medicine

Bug-bite medication

Calamine lotion

Carpal-tunnel wrist supports

Cold medicines

Reading glasses

Cold/hot packs for injuries


Contact lens cleaning solution

Cough drops

Spermicidal foam

Diaper rash ointments

First aid cream/First aid kits

Hemorrhoid medication

Incontinence supplies


Liquid adhesive for small cuts

Menstrual cycle products for pain/cramps

Motion sickness pills

Muscle or joint pain products

Nasal sinus sprays/strips

Nicotine gum/patches for stop-smoking

Pain relievers

Pedialyte for ill child dehydration

Pregnancy test kits

Rubbing alcohol

Sinus medications

Sleeping aids to treat insomnia

Sunburn ointments or creams

Thermometers (ear or mouth)

Throat lozenges

Visine and other eye products

Wart remover treatments


Dual purposes OTC items

The following list of dual-purpose over-the-counter items can be reimbursed if used for medical purposes. They must be accompanied by a medical practitioner’s note stating the item is to treat a specific medical condition and not a cosmetic procedure.

Acne treatment (Retin A) only to treat a specific medical condition such as acne vulgaris

Dietary supplements or herbal medicines to treat medical conditions in narrow circumstances

Fiber supplements under narrow circumstances

Glucosamine/chondrotin for arthritis or other medical conditions

Orthopedic shoes and inserts (only the cost difference between orthopedic and nonorthopedic shoes will be reimbursed)

Hormone therapy and treatment for menopause symptoms such as hot flashes and night sweats

Pills for lactose intolerance

Prenatal vitamins

St. John’s Wort for depression


Weight-loss drugs to treat a specific disease including obesity


Medical expenses eligible for reimbursement under a Section 125 cafeteria plan


Adoption related medical costs

Air conditioner filters for allergy relief (supplied by online Goodman furnace and AC)

Alcoholism treatment

Ambulance services

Attendant for blind or deaf student


Birth control pills

Blind persons accessories (seeing eye dog, Braille training, special schooling)

Capital expenditures (home modifications for handicapped)

Car modifications for handicapped

Childbirth prep classes (mother only)


Christian Science treatment

Contact lenses (including replacement insurance)

Cosmetic Surgery (non-elective only)


Deaf persons accessories (hearing aids, special schooling)

Dental fees


Diagnostic fees

Doctors’ fees

Domestic aid (in home nurse)

Drug addiction treatment

Dyslexia language training

Electrolysis (medical reasons only)

Elevator for cardiac conditions

Eye exams and glasses

Fertility enhancement

Fluoride device

Guide animals

Hair transplant (surgical and medical reasons)

Hearing aids


Hospital care (in-patient)

Indian medicine man


Insurance premiums (medical post-tax only)

Iron lung

Lab fees

Laetrile (legal use)

Laser eye surgery

Lead paint removal

Learning disability (doctor recommended special schooling fees)

Legal expenses related to medical condition

Lifetime medical care prepaid-retirement home

Limbs (artificial)

Lodging (for medical care away from home)

Long Term Care Services (qualified medical only)

Meals (medical care away from home)

Medical conferences (relating to illness)

Nursing home (medical reasons)

Nursing services (home care)

Operation (legal, including abortion)

Organ Donor


Orthopedic shoes


Oxygen equipment

Prescription Drugs –

Psychiatric care


Sexual dysfunction treatment


Stop Smoking Programs (and related stop smoking prescription drugs only)

Swimming pool (for polio or arthritis treatment)

Telephone equipment (for hearing impaired)

Television close caption prescribed by doctor


Weight loss programs (doctor prescribed for medical reasons)


Wigs (alleviation of physical or mental discomfort)


If you have not opted in to your firm’s flex-pay plan, you may want to consider it during the next enrollment period.  Many other items you use regularly may be covered and it is a good way to cut taxes. In many cases it is permitted to add or a portable air conditioner to the plan. Consult the portable air conditioner guide for all the details.

Though some flex pay plans offer an explicit choice of cash or benefits, most today are operated through a “salary redirection agreement”, which is a payroll deduction in all but name. Deductions under such agreements are often called pre-tax deductions because salary redirection contributions are not actually or constructively received by the participant. Therefore, those contributions are not generally considered wages for federal income tax purposes,  nor are they usually subject to Federal Insurance Contributions Act tax (FICA)  and Federal Unemployment Tax Act (FUTA).

So remember to save your receipt the next time you purchase MigreLief and submit it along with a note from your doctor for reimbursement.

~ The MigreLief Team


BUTTERBUR AND MIGRAINE WARNING: If You’re Considering Taking Butterbur for Migraines, Read This Web MD Warning.

September 27th, 2012

Some butterbur products may contain pyrrolizidine alkaloids (PAs), and that’s the major safety concern.

PAs can damage the liver, lungs, and blood circulation, and possibly cause cancer. Butterbur products that contain pyrrolizidine alkaloids (PAs) are UNSAFE when taken by mouth or applied to broken skin. Broken skin allows chemicals to be absorbed into the body. Do not use butterbur products unless they are certified and labeled as free of PAs.

Short-term treatment with Butterbur 

 PA-free butterbur products are considered POSSIBLY SAFE  when taken short-term, by mouth appropriately. PA-free root extracts seem to be safe when used for up to 16 weeks in adults. There is some evidence that a specific PA-free butterbur extract (Petadolex, Weber&Weber, GmbH & Co, Germany) can be safely used in children who are 6-17 years old for up to 4 months.

Not enough is known about the safety of using PA-free butterbur products on unbroken skin. Don’t use it.



PA-free butterbur is generally well tolerated. It can cause belching, headache, itchy eyes, diarrhea, asthma, upset stomach, fatigue, and drowsiness. However, it seems to cause less drowsiness and fatigue than cetirizine (Zyrtec). Butterbur products might cause allergic reactions in people who are allergic to ragweed, marigolds, daisies, and other related herbs.

So please consult your doctor before taking Butterbur for migraine treatment. 


Update on the efficacy and safety of Petadolex®, a butterbur extract for migraine prophylaxis – Dr. Joseph M. Prietto.

NEUROLOGY TIMES – JANUARY 28, 2015  “Migrane Preventative Buterbur Has Safety Concerns”
“…Despite butterbur’s potential efficacy, doubts are increasing about the long-term safety of this supplement given of the risk of liver damage and the lack of an actively regulated preparation. Due to the mounting concerns, the American Headache Society is currently evaluating a position statement cautioning against its use.”

Taking a Closer Look at the Herbal Remedy, Butterbur
May 13, 2014 Alex Mauskop, MD



Migrelief FinalMIGRELIEF

The only multi-patented, physician recommended nutritional supplement for either men, women or children over 12  years of age, who suffer from chronic migraine.

» Buy Now



  • Categories
  • Recent Posts