Causes of Migraines | MIGRELIEF - Part 2

Causes of Migraines Category

Understanding Your Migraine Pain

January 6th, 2015


Pain experience is individual.  Everyone experiences pain differently, due to so many varying factors. Your current state of health, including whether or not other diseases are present, childhood experiences, mood, environment, and previous experiences of pain are all factors in how you experience pain now.

Pain is only good as a warning. According to the Institute of Medicine’s recently released study, “While pain sometimes can serve as a warning sign that protects individuals from further harm, chronic pain is harmful and impairs productivity and quality of life,” as you well know. In the same study (Relieving Pain in America, 2011), 85% of migraine sufferers had at least one significant medical condition (besides the headaches), and 15% of sufferers also reported major depression.

Pain hurts in more ways than one. Pain can produce psychological and cognitive effects — anxiety, depression, and anger. Anxiety occurs because of fear of the recurring pain, depression from the feeling of not being able to escape the pain, and anger at having to deal with the pain in the first place. If allowed to persist, acute pain can become chronic pain which makes physical changes in your body. Pain can become a disease in its own right, and ultimately, it can result in a dysfunction in your central nervous system (CNS).

Are you progressing toward CNS dysfunction? If you suffer from frequent migraines, you may recognize the beginnings of such dysfunction in the form of shadow pain, more frequent headaches, or more triggers from sources which were previously quite benign for you. You may feel as though you live in a frustrating and increasingly hostile world from which you desire to retreat. Your work, and thus your livelihood, may be impacted or threatened by frequent absences. The ball rolls on, continuing to take its toll on even your basic enjoyment of life. “Research,” reports the IOM study, “has shown quality of life [for migraine sufferers] to be inversely proportional to the frequency of migraine occurrence.”

Prevention is crucial. This is why pain management and the role of prevention is so crucial to restoring quality of life for the migraineur. While the medical community currently focuses on abortives (medications to rid the sufferer of immediate pain) and palliation (making one comfortable in the midst of pain), the IOM stresses the importance of understanding triggers, conditions, and causes of the pain, along with preventive treaments, in order to eliminate the outcomes of chronic pain — that physiological change that occurs with chronic suffering.

You can stop pain’s progress. The good news is that even if those changes have already occurred, there are measures you can take to reverse the changes. Although it will be a difficult path, the reward is stopping the progress of chronic pain as disease, healing your body, and drastically reducing the incidence, and even possibly the complete cessation of the headaches.

If your headaches have not progressed to point of morbidity, you can take measures to prevent your headaches from progressing from acute to chronic.

If you are currently a chronic migraine sufferer, you too, are a great fit for migraine prevention.

The Road to Preventing Migraines

The most important step to lifelong migraine relief is prevention. Prevention includes understanding and resolving the underlying cause(s) of the headaches. This helps one to avoid the environment or the set of triggers for headache pain to occur in the first place, or, having experienced pain in its acute form, to prevent the pain from becoming chronic.

Migraines can be prevented.  NPR (National Public Radio) published a June 2012 article about the fact that there are migraine preventives, but their statistics show that only between 3 and 13% of people use preventives. According to conventional medicine, 38% of migraines can be prevented. Natural medicine practitioners know that many more than that can be prevented.

Dr. Jamie Von Roenn and her associates said in 1993, “For at least two decades, most major medical journals and the lay media have recognized that many patients have needless pain.” Dr. Von Roenn has been a pioneer in palliative (pain relief) medicine. Another decade has passed since she made that statement.

Migraine experience is individual. Despite many years of research and observation, the medical community has never “officially” determined exactly what causes migraines. Part of that is due to the individual nature of the experience. While there are common triggers, symptoms, and patterns, the underlying cause is extremely complex and individual. The most that the medical community has been able to determine concretely is that the majority of migraineurs have a family history of migraineurs. Fully 85% of migraine sufferers have a family member who also suffers or has suffered from migraines.

Lack of scientific determinates, however, does NOT prevent a fuller understanding of the phenomena by both user and intuitive practitioner. (Use of the term “intuitive” here implies any member of the medical community who applies intuition and analysis, in addition to empirical knowledge, in order to understand a medical phenomenon.)

There are several avenues toward prevention.  You are your own best advocate. Only you know how you experience your migraine pain. Only you have the key to your personal headache “structure,” all of the elements that go into creating your migraines. According to the 2011 IOM (Institute of Medicine) study, a gamut of “upstream” influences shape conditions and behaviors that produce or exacerbate disease, in this case, your pain. It appears that, although there may be specific pain triggers, that the entire milieu surrounding your migraines may be more complex.

Commit to the discovery process. Prevention requires work, self-study and analysis, and a willingness to apply what is learned. The ultimate goal, of course, is to eradicate the headaches entirely, but how does one do that if they keep occurring during the discovery process, and they begin to escalate? One answer is to treat with a preventive remedy while working to discover the root causes. While the easiest thing may be to take an abortive (something to stop the pain), abortives are rarely natural, and side-effect pharmaceutical abortives may cause far more problems than they solve.

Consider starting with MigreLief – The immediate goal is to reduce the incidence of the migraines. Cutting migraines by half, say from a dozen migraines a month down to six or three is huge. The triple therapy of MigreLief can help achieve this, and can possibly eliminate them all together. Using MigreLief during the discovery process could stop your headaches from progressing, enabling you to concentrate more on finding and eliminating causes.

Migraines should not be a lifestyle. Take control, consider prevention over treating the symptoms of migraine pain for life.


Curt Hendrix M.S. C.C.N. C.N.S is the chief science officer for both Akeso and Concourse Health Sciences, a pharmaceutical company developing prescription drugs from natural compounds. Mr. Hendrix has been named as the Principal Investigator in multiple National Institutes of Health (NIH) governmental grants studying the benefits of natural medicines on disease.Formed in 1992, Akeso is a professional, natural medicine/dietary supplement company. Over the last 15 years MigreLief has helped hundreds of thousands find solutions to the pain and suffering of debilitating migraine headaches. Two international patents have been granted covering the unique MigreLief formulation.

The information on this Website is for educational purposes only and is not intended to replace the advice of physicians or health health care practitioners. It is also not intended to diagnose or prescribe treatment for any illness or disorder.

Find out more at – See blog for more health information and coupons

Breaking The Cycle of Rebound Headaches Caused by Excessive Use of Prescription Drugs

August 4th, 2013

Medication Overuse Headache- (MOH) – A big dilemma.

The following comment is from Stephen Silberstein, M.D.,  director of the Jefferson Headache Center and professor of neurology, Thomas Jefferson University in Philadelphia

“One of the greatest bugaboos we see every day in headache centers is patients with chronic daily or near-daily headache, who are overusing medication. It is our most common problem. These patients have often not responded to treatment and in an attempt to treat themselves, actually make the problem worse. This is not addiction or an attempt to get ‘high’; rather, it is motivated by the patient’s desire to relieve pain and dysfunction. Migraine preventive therapy is grossly underused.”

Do you find yourself taking more and more medications to try to keep your migraines/headaches under control? Do you find that one or two days after taking your medications that your headaches return?  Do you use more than three triptan drugs a week?  Are you taking OTC drugs 15 days or more out of every month?

If your answer to any of the above questions is “YES”, then you may very well be suffering from Medication-Over-Use-Headaches.  The drugs you are taking are actually causing you to experience more headaches, even if they temporarily help the headache at hand.

Triptans, ergot drugs, opiates (morphine, codeine, meperidine (Demerol), oxycodone (Oxycontin) (Butorphanol) and OTC pain pills can all cause medication over-use headaches (MOH). If people use 3 or more triptans a week they will probably get rebounds, the same for opiates and if they are using Excedrin or other OTC pain pills 12-15 days a month or more, they will be at higher risk for rebound headaches as well.



Research has shown that withdrawing (detoxing) from these drugs can in many cases reduce the total number of headaches you experience as well as the intensity of those headaches.  Withdrawal is not easy and the symptoms of withdrawal can be challenging, but the results are definitely worth it for most sufferers.

For triptans, the detox period during which there may be withdrawal symptoms, like continuing headaches, nausea, vomiting, and disrupted sleep will last about 4-5 days on average. 

The symptoms may last up to 8-10 days for withdrawing from opiates, ergots or OTC drugs.

The literature and research states that it is important to start taking a preventive treatment product prior to or at the same time you start the detox program. (see www.MIGRELIEF.COM) We recommend starting MigreLief one week before withdrawing from the drug that is being over-used.

Keep a rescue pain medication available that is different from the medication that has been over-used, for emergency situations, only!


If withdrawing from OTC medications, keep a triptan or opiate drug available for an emergency rescue situation only. 


At the end of 5-10 days, depending upon what medication you are withdrawing from, you should find that your rebound headaches have significantly diminished or disappeared.

Your use of the offending medication should be either eliminated or substantially reduced.  Be sure to keep taking MigreLief daily because preventive products are very important to the success of this program.  Continue to take  MigreLief to maintain the benefits you have achieved.  


To the Best of Health,


Curt Hendrix, M.S., C.C.N., C.N.S.

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 WARNING: The above recommendations are based upon review of some literature discussing detoxing or withdrawing from drugs causing Medication-Over-Use-Headaches. It is for education purposes only. It is not a substitute for medical advice. It is necessary to discuss your particular situation with your physician before starting on this kind of program.


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Menstrual Migraines in Adolescents

August 1st, 2013

Many adult women who suffer from chronic migraine headaches find that many, if not most of their headaches occur between 2 days before menstruation and 2-3 days after menstruation. These migraines are referred to as “menstrual” or hormonally related migraines.

Recently researchers at Cincinnati’s Children’s Hospital completed a study analyzing what percentage of adolescent, menstruating young women experienced “menstrual” or “hormonally” related migraines.

It was found that out of the 891 adolescent girls studied, 50% experienced a headache during their first period upon entering puberty and almost 40% of these adolescents continued to experience migraines just before or just after their periods.

These migraines are brought about by both the hormonal shifts that occur during menstruation as well as changes in blood sugar levels. They are often accompanied by PMS symptoms of bloating, breast pain, irritability, cravings, acne, poor sleep and anxiety, as well.

Correcting these imbalances can reduce or eliminate both migraines and many of the symptoms of PMS.

Our own clinical observations indicate that addressing hormonal shifts without also balancing blood sugar levels leads to less comprehensive benefits not only regarding migraine prophylaxis but regarding the afore mentioned symptoms associated with PCOS. Therefore we recommend adding to any proposed regimen, ingredients like chromium picolinate, or other insulin sensitizing ingredients, plus additional dietary fiber to prevent spiking of blood glucose levels that can often lead to the precipitous drops associated with hypoglycemia.

We at MigreLief have created a safe, gentle and natural medicine for adolescent and adult women suffering from both/either menstrual/hormonally related migraines and monthly symptoms of PMS, it is called MigreLief+M. It will be available in 1-2 months. We will announce it’s availability on our Twitter, Face book and MigreLief blog sites.

>To your good health,

Curt Hendrix M.S. C.C.N. C.N.S.
Chief Science Officer, Akeso Health Sciences L.L.C.

Riboflavin – Health Benefits & Migraine Prevention

July 19th, 2013

Migraine Ingredients MigreLief Riboflavin, Feverfew and MagnesiumMultiple studies have demonstrated that high dose riboflavin can reduce the frequency and intensity of migraines in both adults and children.


Riboflavin also known as Vitamin B-2, is an essential nutrient required for life. One of the most important uses of riboflavin is that it helps in the production of energy in the body.  The vitamin is water soluble, which means the body cannot store it, but it is vital for red blood cell production and growth.

Carbohydrates, fats and proteins all interact with riboflavin when releasing energy for our bodies to use. Riboflavin also acts as an antioxidant which can prevent premature aging and chronic illness.

It’s naturally found in organ meats such as liver and kidney and in many vegetables, legumes, nuts and leafy greens like spinach. Some of the richest sources include calf liver, torula yeast and brewer’s yeast, while almonds, wheat germ and mushrooms, milk, cheddar cheese and eggs are also good sources.



– Riboflavin is involved in energy production in every cell.

– Riboflavin helps convert carbohydrates to sugar which acts as fuel to carry out bodily functions.  It is also critical to the breakdown of fats and proteins into energy your body can use. The enzymes involved in energy production do not function optimally without adequate riboflavin in the diet, which may lead to fatigue.

– Riboflavin is an excellent antioxidant which protects your body from free radical damage and aids in slowing the process of aging and many chronic diseases.

– Riboflavin is essential for the formation and proper functioning of fresh red blood cells. It interacts with iron which is used to synthesize hemoglobin (a major component of oxygen-carrying red blood cells.) Keeping hemoglobin levels high, helps your body to get the oxygen-rich blood necessary to perform the daily functions of life.

– Riboflavin is essential for the growth of healthy body tissue, including skin, hair, nails, and connective tissue. (One of the most common signs of riboflavin or vitamin B-2 deficiency is scaly, dry skin, cracked lips and lesions around the mouth.)

– Riboflavin ensures proper growth and healthy reproductive organs

– Riboflavin helps to maintain a healthy immune system by enhancing the natural immunity by strengthening the antibody reserves and by reinforcing the defense system against infections.

– Riboflavin protects the nervous system: Vitamin B2 can help in treating various nervous system conditions such as multiple sclerosis, anxiety and epilepsy.

– Riboflavin helps to prevents acne. It helps improve the mucus secretion of skin and might clean up the skin pustules.

– Riboflavin (B-2) also plays a major role in the functioning of the other B complex vitamins like vitamin B3 (niacin) and vitamin B6 (pyridoxine). Therefore, lack of riboflavin in the body can hinder the activity of other vitamins.

– Riboflavin is used in iron therapy for the treatment of sickle cell and iron deficiency anemia.

– Riboflavin may lower the risk of cataract in people.

– Riboflavin helps in the repair of tissue, healing and infection

– Riboflavin assists in regulating thyroid activity.

– Riboflavin helps prevent conditions like rheumatoid arthritis, eczema, acne, and migraines.


Image Mother - Daughter - New Life MigreLief for MigrainesRIBOFLAVIN  &  MIGRAINE PREVENTION

Riboflavin/B-2 metabolites such as Flavin Adenine Dinucleotide or “FAD” are co-factors in the Krebs Cycle that produces energy. This coenzyme is an important component of the electron-transport chain.   This is crucial because a deficiency of mitrochondrial energy reserves has been observed in migraine sufferers and many people exhibiting poor cerebrovascular tone.  Furthermore, migraineurs experience significant mitochondrial energy deficiencies prior to a migraine.  Replenishing them with high dose ribolavin helps to avoid migraines.

Note: “Flavin” refers to any of a group of yellow nitrogen-containing pigments, as riboflavin, that function as coenzymes. Because the vitamin riboflavin is water soluble and not stored in the body, excess riboflavin not utilized by cells in the body is safely eliminated through the urine causing it to turn yellow.

MigreLief provides 400mg of Riboflavin, which is significantly higher than most multi-vitamins or B-complex products.

Multiple studies have demonstrated that high dose riboflavin can reduce the frequency and intensity of migraines in both adults and children.  While women suffer migraine attacks three times more than men, both men and women equally benefit from riboflavin treatment.

The Journal of Headache & Pain reported on  the results of a study; Riboflavin Prophylaxis in Pediatric and Adolescent Migraine,  “… In conclusion, riboflavin seems to be a well-tolerated, effective, and low-cost prophylactic treatment in children and adolescents suffering from migraine.”

(J Headache Pain. 2009 Oct;10(5):361-5. Epub 2009 Aug 1. – Riboflavin prophylaxis in pediatric and adolescent migraine – Condò M, Posar A, Arbizzani A, Parmeggiani A, Department of Neurological Sciences, University of Bologna, Bologna, Italy.)


Riboflavin – Magnesium – Fevefew

Nutritional deficiencies, inflammation and vasospasms can independantly and togehter contribute to migraines occurring.  While riboflavin can be effective at reducing migraine attacks, combining riboflavin with magnesium and feverfew provides three mechanisms of action, each working independently and together in a triple therapy approach to battling migraine disorder.  All 3 are listed in the “American Academy of Neurology’s Evidence Based Guidelines For Migraine Prevention
(Superior Efficacy of Puracol Feverfew™)  (Magnesium Helps with Much More than Migraines

In fact, a 2003 study in the Journal of the American Nutraceutical Association noted that using riboflavin in combination with feverfew and magnesium, helps to maintain normal cerebrovascular function aiding the blood to flow more properly in the brain. When the blood is flowing the way it should, it can prevent sudden spasms and decrease inflammation, resulting in the prevention of migraines.

MigreLief – Triple Therapy with Puracol

Magnesium Feverfew and B2 Riboflavin for my Chronic Migraines

Making a difference in the lives of migraine sufferers worldwide since 1996, MigreLief  Triple Therapy with Puracol™ comes in 3 formulas to meet everyone’s needs;  Original, Childrens (age 2-11) and +M (menstrual/hormonal migraines.)  Visit for more information.

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JUNE is Migraine Awareness Month… Children Get Chronic Migraines Too! Pediatric Migraine Facts:

May 28th, 2013

2013 Migraine Awareness Month - Children with Migraines

Many people don’t know that children also get migraines.  Every day millions of parents watch helplessly as their children suffer from debilitating migraine attacks.

Migraines in children often go undiagnosed because unlike adults, children can not easily communicate to their parents or physicians just what type of symptoms they’re experiencing.

Many times they’re too young to articulate what they’re feeling so migraines go untreated for a long time.  In many cases crying, lack of focus  and symptoms of depression are attributed to things other than the actual problem.

Fortunately children who suffer chronic migraines are great candidates for prevention.


Migraines interfere with all aspects of a child’s life, cause permanent changes in the brain, and can lead to increased risk of depression.  Because it can be difficult for children to convince their parents or teachers that they are really sick, their attendance in school and academic achievement may suffer making it difficult to catch up and adding more undue stress to their lives.


– A migraine is a type of severe, incapacitating headache that can strike suddenly and often with accompanying symptoms of nausea, abdominal pain and vomiting.   They are often recurrent.

– About one out of every 10 kids, or nearly 8 million children in the United States alone are plagued by what has become the most common acute and recurrent headache pattern experienced by children today.

– Migraines may occur with or without aura and last in children from 30 minutes to 48 hours. (Migraine aura is the collective name given to the many types of neurological symptoms that may occur just before or during a migraine such as visual, sensory, motor or verbal disturbance.)

– Common precursors and symptoms of child migraine; cyclical vomiting, abdominal migraine pain, vertigo, and sensitivity to light.

-Approximately 20% of children with migraines have their first attack before the age of 5.

-Approximately 20% of adult migraine sufferers report onset before age 10.

-Migraines are more common in boys than girls until girls begin menstruation

– Migraine in children can differ from migraine in adults. Non-headache and neurological symptoms (aura) may be more prominent than the headache.

– Child Migraine is often underdiagnosed by doctors, possibly due to the prominence of non-headache symptoms

The Four Stages of Migraine Headaches

Migraines often progress through four stages. Your child may or may not have all four stages. And the stages may not be the same every time a migraine occurs.

  • Prodrome. In this early stage, your child may feel tired, uneasy, or moody. It may be hours or days before the headache pain begins.
  • Aura. Up to an hour before a migraine, your child may experience an aura (odd smells, sights, or sounds). This may include flashing lights, blind spots, other vision problems, confusion, or trouble speaking.
  • Headache. Your child has pain in one or both sides of the head. Your child may feel nauseated and have a strong sensitivity to light, sound, and odors. Vomiting and/or diarrhea may also occur. This stage can last anywhere from 48-72 hours.
  • Postdrome or recovery.  For about a day after the headache ends, your child may feel tired, achy, and exhausted.

What Causes Migraine Headaches?

It is not clear why migraines occur. If a family member has migraines, your child may be more likely to have them. Many people find that their migraines are set off by a “trigger.” Common migraine triggers include:

  • -Chemicals in certain foods and drinks, such as aged cheeses, luncheon meats, chocolate, coffee, sodas, foods containing MSG. etc.
  • -Chemicals in the air, such as tobacco smoke, perfume, glue, paint, or cleaning products
  • -Dehydration
  • -Not enough sleep
  • -Hormonal changes in the body during puberty
  • -Environmental factors, such as bright or flashing lights, hot sun, weather or air pressure changes

What Are the Symptoms of Migraine Headaches?

Your child may have some or all of the following symptoms:

  • -Pain, often severe, occurring in a specific area of the head (such as behind one eye)
  • -Aura (odd smells, sights, or sounds)
  • -Nausea and/or vomiting, or diarrhea
  • -Sensitivity to light or sound

How Are Migraine Headaches Prevented and Treated?

The goal is to try to stop a migraine headache in its early stages.

  • Work with your child to learn his or her triggers. Then, you can talk about ways to avoid these triggers when possible.
  • Have a nonsteriodal anti-inflammatory drug (NSAID), such as ibuprofen, available to your child at all times. This includes during school and after-school activities. If your child feels the prodrome or aura stage of migraine, he or she should take the NSAID right away. (Be sure your child follows the dosage instructions given by the health care provider.)

If your child’s headache pain has already started:

  • Give the child a dose of an NSAID  such as Ibuprofen
  • Have him or her lie down in a dark, quiet room.
  • Apply a cold compress over your child’s face and eyes (if your child wishes).
  • Have your child stay quiet and still until the pain goes away.

Call your child’s health care provider right away if your child has any of the following:

  • Fever and stiff neck with a headache
  • In an infant under 3 months old, a rectal temperature of 100.4°F (38.0°C) or higher
  • In a child 3 to 36 months, a rectal temperature of 102°F (39.0°C) or higher
  • In a child of any age who has a temperature of 103°F (39.4°C) or higher
  • A fever that lasts more than 24-hours in a child under 2 years old, or for 3 days in a child 2 years or older
  • A seizure caused by the fever
  • Headache pain that does not respond to NSAIDs
  • Headache pain that seems different or much worse than previous episodes
  • Headache upon awakening or in the middle of the night
  • Dizziness, clumsiness, or other changes with a headache
  • Migraines that happen more than once a week or suddenly increase in frequency


Why you should control your child’s migraines NOW rather than later:

Researchers are discovering “migraines beget migraines” – the more migraines one has, the greater the tendency for future migraines. Evidence shows an increased sensitivity after each successive attack, eventually leading to chronic daily migraines in some individuals. In order to avoid a lifetime of migraines, it is imperative to lower the frequency and intensity of migraines as soon as possible.

Bottle of Children's MigreLief
Why Children’s MigreLief should by your first choice:

Comprehensive Support for Neurological Health with a Proven Track Record

Formulated to address the problem, not just treat the pain, Migrelief is guaranteed to make a difference, whether your child’s migraines are classic, common, abdominal or complicated (basilar, hemiplegic, etc.)

MigreLief Benefits

-Longterm relief as opposed to temporary relief

-Safe and effective for children over the age of 2

-Two international patents have been granted the unique MigreLief formulation

-Recommended by pediatric neurologists

-NO harmful side-effect

-MigreLief’s Triple Therapy™ Ingredients: a vitamin, a mineral, and an herb (Magnesium, Riboflavin (Vitamin B-2) and a proprietary form of the herb Feverfew) have been proven effective

-All 3 ingredients are listed in The American Academy of Neurology’s Guidelines for Migraine Prevention.

-Taken daily as a dietary supplement

-Formulated to address the underlying nutritional deficiencies and imbalances that can cause migraines and that many children sufferers have in common.

-Maintains the already normal cerebrovascular (blood vessels in the brain) tone and function your child has on migraine free days

-Used by thousands of children worldwide and hundreds of thousands of adults.

-Guaranteed to make a difference!

Note:  Children’s MigreLief  is safe and gentle for children ages 2-11 and Original MigreLief is for kids ages 12+  Either MigreLief may be crushed and taken with applesauce, yogurt etc. for those children who are unable to swallow caplets of any size.

MigreLief Migraine Prevention Coupon

Act Now Before Your Menstrual Migraines Become Chronic Migraines

March 20th, 2013

Menstrual Migraine Relief & Menstrual Migraine PreventionMigraines that start around the menstrual cycle can often become chronic.  Don’t wait for that to happen.  Do not let menstrual migraines become chronic migraines! Studies show menstrual migraines are often more severe, last significantly longer, and are more resistant to treatment than usual non-menstrual migraines.  Medications that are currently on the market used to stop migraines can increase the frequency and tendency of migraine attacks, making sufferers more dependent on the medication.

Stopping menstrual migraines BEFORE they occur or reducing the frequency is imperative for restoring quality of life and for avoiding additional health problems.


Learn More About Menstrual Migraine

The quality of life for menstrual migraine sufferers is often significantly diminished, affecting education, careers and social activities. This can lead to:

  • Depression
  • Anxiety
  • Insomnia

 Menstrual related migraines are different than the usual non-menstrual Migraine attacks. According to a study published in the medical journal Cephalagia:

  • They are typically more severe, last significantly longer AND are more resistant to traditional treatments
  • An average menstrual migraine lasts nearly 23.4 hours compared to 16.1 hours for non-menstrual migraines
  • Menstrual migraines cause more disability and inability to function- interrupting daily responsibilities
  • Medications used to treat the pain are 50% less effective for menstrual migraines
  • Even when the pain medication did work, the risk of the menstrual migraine reoccurring was much more likely

When medications don’t work, or the OTC pain medications taken to treat the pain work only temporarily, patients take more drugs and get caught up in a vicious cycle of Medication Overuse Headaches (MOH). 


According to Stephen Silberstein, M.D., director of the Jefferson Headache Center, professor of neurology at Thomas Jefferson University in Philadelphia and one of the most published migraine neurologists in the country, “One of the greatest bugaboos we see every day in headache centers is patients with chronic daily or near daily headaches, who are overusing mediation.  It is our most common problem.  These patients have often not responded to treatment and in an attempt to treat themselves, actually make the problem worse.  This is not addiction or an attempt to get “high”, rather, it is motivated by the patient’s desire to relieve pain and dysfunction.”  He added“Migraine prevention is grossly underused.”


Furthermore, according to Neurologist Jan Brandes, the founder of the Nashville Neuroscience Group, “We’ve begun to see from research that the frequency of migraine attack is linked to permanent changes in the brain, and I think that changes the playing field for patients and those taking care of them.  We really need to think carefully about how to control the frequency of attacks and really need to do it earlier rather than later.

Chronic migraines not only take you away from the life you love, they can lead to overuse of side-effect prone drugs, depression and an increased risk of stroke.

Prescription medications available to treat the pain of a migraine come with a long list of side effects with just some including:

  • Nausea
  • Fatigue
  • Depression
  • Insomnia
  • Weight gain
  • Decreased libido
  • Dizziness

These medications can often leave the sufferer just as unable to function as the pain of the menstrual migraine; therefore, PREVENTION is crucial.


Manage your migraines before they manage you!  

Thousands of women have taken their lives back with MigreLief. The ingredients in MigreLief+M have been CLINICALLY PROVEN to control fluctuating hormones, blood sugar swings and menstrual-related migraines.

Until MigreLief+M, no one medicine was available to manage both hormonal and blood sugar fluctuation and provide relief for all of the feminine related issues such as migraines, PMS & PCOS symptoms:


Cravings Bloating Depression Breast Pain Difficulty Concentrating
Irritability Weight Gain Acne Infertility Irregular Menstrual Cycles



Just a few of the unsolicited comments received from women, like you, who had been needlessly suffering each month but restored their quality of life through MigRelief+M include:


“It is an absolute lifesaver for me!  I recommend it to all of my friends who have migraines!  ~ Pam K (Facebook Fan) “I am ecstatic to report that I have been migraine free since I started using MigreLief last December.  Thanks for making such an outstanding product!”  ~ Michelle G. (Facebook Fan)


“I’ve been taking MigreLief for a little over a year now. I just wish I’d found it sooner. I’ve suffered with chronic migraines for 29 years my first being right after my youngest daughter was born. Last year it had gotten to the point I was having migraines that would last for days without end, and I nearly lost my job because of all the work I was missing. I heard about MigreLief from my Neurologist, decided to give it a try, and noticed a difference within the first 4 days. I hated the side effects from all the drugs my doctor had prescribed for me, and I still had migraines. I still occasionally get a migraine, but nothing compared to what I had been living with for so long. MigreLief has been a life saver for me. It gave me back my life. I love it and I recommend it to everyone who suffers with migraines. The best part is there aren’t any drugs involved.” ~Rita M. 


Take the first step in getting your life back NOW, don’t wait for the pain to return! MigreLief+M is your best option!


Menstrual Migraine treatment

RISK FREE OFFER:  We are so confident MigreLief+M will work for you, we offer a 100% satisfaction guarantee if you try it for 90 days (each bottle is a one month supply.)  Although many people have experienced positive results in much less time, we recommend 90 days to build blood levels for maximum effectiveness.  Nutritional deficiencies, inflammation and vasospasm can independently and together contribute to migraine occurrence, frequency and intensity.  MigreLief  is a “Triple Therapy” approach to maintaining normal cerebrovascular tone and function by addressing the underlying nutritional deficiencies, and imbalances many migraine sufferers have in common.


MigreLief Facts:

  1. Available in 3 formulas:  Original, Menstrual/Hormonal, Children’s
  2.  Recommended by Neurologists and other healthcare professionals
  3.  No harmful side-effects.
  4.  May be combined with all other migraine medications.
  5.  Empowering migraine sufferers worldwide since 1996
  6.  Formulated and patented by Scientist Curt Hendrix, M.S., C.C.N., C.N.S.
  7.  Named principal scientific investigator in multiple NIH (National Institutes of Health) governmental grants to study the effects of natural medicine on disease.


**DISCLAIMER: (MigreLief) is not intended to diagnose, treat, cure, or prevent any disease or illness.


Prevent Menstrual Migraine While Avoiding Middle Age Weight Gain

August 18th, 2012

MigreLief +M Menstrual Migraine ControlLONG TERM MENSTRUAL MIGRAINE RELIEF

Prevent menstrual migraine headaches by addressing the underlying causes leading to more than just migraines.


90% of women gain weight between the ages of 35-55. The average weight gain is about 15-20 pounds, with a disproportionate amount of this weight being an increase in body fat.

What is unfair about this, is the fact that much of this weight gain and/or body fat increase, can occur without, increasing caloric intake. This is different than the weight you gain because you eat too much of the wrong foods and don’t exercise enough. It’s the stubborn, difficult weight gain or increases in body fat percentage (without weight gain) that occur in middle-aged and beyond women.

Why does this phenomenon occur in so many women in this age range, and what can you do to prevent or reduce the good chance this may happen to you?

There are specific techniques and natural supplements that can help balance a female body that is desperately trying (and in many cases with limited success) to balance many physiological processes, that by design, change with age. These changes can cause uncontrolled and undeserved weight or body fat percentage gains.

Much of this new weight will NOT be gained as much around the hips and thighs but in the stomach and waist area. Shifting/fluctuating hormones, stress and insulin resistance are the guilty parties.

Women who suffer from migraines will also be glad to learn that controlling these same issues of fluctuating hormones, stress and blood sugar due to insulin resistance will reduce their migraine frequency and intensity as well.

Why does this weight gain occur when hormones fluctuate and stress and blood sugar are poorly controlled?

Some women can start experiencing the symptoms of early menopause (perimenopause) as soon as their mid 30’s. The hormonal fluctuations of perimenopuase and the few years after menopause (one full year with no period) can strongly influence your metabolism, appetite and increase your storage of fat.

Though your hormones will fluctuate during perimenopause, the general trend is for your estrogen levels to diminish with ultimately the cessation of ovulation.

The body is aware of decreasing levels of estrogen from the ovaries and searches for new sources of estrogen production. Unfortunately, fat cells are a source of estrogen and the body may convert more calories into fat.

Though progesterone levels also tend to decrease during this period, decreasing progesterone levels don’t cause weight gain but they may cause water retention making you feel puffy or bloated.

Testosterone levels may also decrease during perimenopause (and menopause). This could result in decreased muscle mass (as well as other things like decreased libido). Less muscle mass would lead to decreased metabolic rate and additional possible weight gain.


As if dealing with fluctuating hormones isn’t enough of a challenge during these years of a woman’s life, both men and women (in ever increasing numbers, mostly due to diet) are becoming “insulin resistant”.

This is a condition where your body is no longer as responsive to the hormone insulin, as it was when you were younger. Our bodies require increasing amounts of insulin to be released to maintain blood sugar at healthy, non-diabetic levels. Insulin resistance can occur whether you are over-weight or thin.

When our bodies don’t respond in a sensitive way to insulin, the sugar in our blood, is not absorbed efficiently by our cells and they don’t get the source of energy that they need. The cells can feel deprived and appetites increase and fat accumulation and weight gain can occur.

In the case of women suffering from PCOS (Polycystic ovarian syndrome), the insulin resistance that accompanies this condition leads to weight gain as well. But in the case of PCOS the women often have too much testosterone and this causes the weight gain to occur around the stomach and waist much like it does it men. Also hair at the crown of the head can thin, and hair may grown on the face and back.

In fact, because estrogen and progesterone levels drop more than testosterone levels do during perimenopause and menopause, women may also tend to gain more around the middle than the hips and thighs. Some women tend to lose their waistline.

The fat that you can grab around your belly is NOT the problem. This is just sub-cutaneous fat, and though cosmetically not desirable, it is not the fat that increases cardiovascular and cancer risk.

It is the fat beneath your abdominal muscles that surrounds your internal organs that is of greater health concern. This fat is called abdominal or visceral adiposity.

It is the fat that protrudes out some men’s stomach to the point where they look like they swallowed a beach ball but yet they continue to say………. “Feel how hard my stomach is!” Of course it’s hard, there is so much fat underneath the abdominal muscles, pushing them outwards, that or course the abdomen feels hard.

Insulin resistance as well as stress and hormonal fluctuations can successfully be controlled and reversed and your body, self-image, emotional status, energy levels, cognition, health and over-all life will improve dramatically.

How do you know if you are insulin resistant?

One measurement is to measure yourself around the smaller part of your waist (but do NOT suck your stomach in when taking this measurement). Then measure your hips around their widest part.

Divide the waist measurement in inches by the hip measurement in inches. If the resulting number is .8 or larger (for women, 1 for men), then you have disproportionate weight in the waist and are at greater risk of having insulin resistance.

Your risk further increases if you have hypertension, low HDL levels (below 45 if you are a woman), or high triglyceride levels (above 150).

If you have darkened skin patches around the neck or armpits, it is extremely likely that you are insulin resistant. This is a condition known as acanthosis nigricans.

Stress The effects of long-term stress on our over-all health is very significant. One of the most important hormones that is released by our adrenal glands when under-stress is cortisol. This is necessary and helps us to deal with short-term stressful events or stimuli.

But, when stress is chronic, and cortisol is being released in excessive and lasting amounts, it can also lead to weight gain and other health problems.

Like insulin resistance and hormonal fluctuations, stress must also be dealt with.

Bringing It All Together

Because stress, hormonal fluctuations and blood sugar fluctuation due to insulin resistance are also major contributors to chronic migraine headaches as well as weight gain, several of the key “natural medicines” that help to resolve these issues are in MigreLief+M. This is a very effective natural medicine that helps to prevent migraine headaches and coincidentally helps women with the related weight gain issues we have been discussing.

Chasteberry – A specific extract of Vitex Agnus Castus, otherwise known as Chasteberry extract has been shown in numerous human studies to naturally balance the hormonal fluctuation discussed above.

Biotin – Doses of biotin, (a B-vitamin) much higher than normally found in multi-vitamin products, has been clinically proven to help regulate blood sugar irregularities that can be caused by insulin resistance.

B-6 – High doses of Vitamin B-6 have been shown to decrease or eliminate the symptoms of PMS (including bloating and related weight gain) caused by fluctuating estrogen levels. This vitamin is also involved in the processing of sugar and can help protect against the effects of blood sugar fluctuations caused by insulin resistance.

L-Theanine – an amino acid derived from green tea, has been shown to be very calming and help to reduce stress levels.

All four of the ingredients are found in the correct, therapeutic doses in MigreLief+M. For those of you who don’t suffer from chronic migraine headaches but do want to benefit from their weight gain/loss/body fat benefits, I suggest that you purchase these ingredients separately at your health food store.

For those of you who fear that they are insulin resistant, I suggest taking these other ingredients as well (which also can be purchase at any well stocked health food store):

800 mcg per day of chromium picolinate for blood sugar control 600 mg per day of R-Lipoic acid for blood sugar control

Consumption of a least 50 grams of dietary fiber spread out throughout the day with meals. Fiber helps to slow the body’s absorption of sugar and prevents the fluctuations that we have been talking about. You can choose psyllium as a supplement or, ground flax seed as your fiber source.

Moderate aerobic exercise of 20-30 minutes a day can also help to correct insulin resistance.

A daily B vitamin complex of 50 mg of B-1,2,3,5 plus folic acid and B-12 can also help with sugar metabolism and stress.

Diet-wise, lean meats, high fiber whole grains, vegetables, legumes and fruit will help reestablish normal insulin levels. Until you see weight and or body fat starting to drop, keep carbohydrates in the form of pasta, bread and sugar to a minimum.

What to expect?

By following this advice over the course of 3-6 months (3 months or less for migraines) your:

1- Weight or body fat percentages should start to meaningfully drop

2- Your hair, at the front and crown of your head, if it was thinning, should start to thicken

3- Any discolored patches of skin around the neck and armpits should start to lighten or disappear

4- Migraine frequency and intensity (if you were a sufferer) should noticeably improve

5- Energy levels should noticeably improve

6- If you are still menstruating, your periods should be much more regular

7- If you were experiencing perimenopausal symptoms, they should improve

8- If you had unwanted hair on the face or back, it should lighten and thin, if not completely go away.

To read more about some of the natural medicine ingredients written about above and to discover how yo can prevent migraines and lose weight at the same time visit:


Curt Hendrix, M.S. C.C.N. C.N.S



We are so confident that MigreLief will work for you, we are offering a 100% money back guarantee if you are not satisfied with your results for any reason after trying MigreLief for 90 days.  (each bottle is a 1 month supply)

You have nothing to lose but your migraines! 

Let MigreLief make a difference in your life as it has for tens of thousands of users for the past 15 years. 

Note:  MigreLief can be used by itself or safely in conjunction with other migraine medications and prescription drugs.

No side-effects.



Curt Hendrix, M.S, C.C.N, C.N.S, is the Chief Science Officer for Akeso Health Sciences, the manufacturer of the highly successful, comprehensive migraine prevention supplement “MigreLief Triple Therapy with Puracol,” for which he is best known.  Curt formulated MigreLief in 1996 and is dedicated to the research and development of natural medicines for specific medical conditions and innovative, leading edge solutions for migraine sufferers worldwide.

He has been named  Principal Scientific Investigator in multiple National Institutes of Health (NIH) governmental grants studying the benefits of natural medicines on disease.

He is currently working under an NIH grant and principal investigator for research and development of  his all natural combination drug for arresting the development of Alzheimers disease.

Phases of Migraine Explained ! Techniques to Outsmart Your Migraine Headache

August 9th, 2012

There are 4 distinct phases to a migraine:  Prodromal (aka Premonitory), Aura, Pain and Postdrome

It is during the first two phases (prodromal and aura) that you get hints that a migraine is coming, and recognizing these hints (symptoms) may give you the edge you need to fight back and either prevent the migraine entirely or decrease the severity and or duration of the pain phase (which is obviously the most debilitating and problematic).

The Prodrome Stage – About 65% of migraine sufferers experience the prodrome phase. In the prodrome stage, sufferers experience emotional or physical symptoms two hours to two days before the pain phase starts.

These symptoms can occur in migraineurs with and without aura.

They are:

  • Fatigue
  • Yawning
  • Appetite changes
  • Altered mood – depression
  • Muscle Stiffness – especially in the neck
  • Appetite changes
  • Digestive changes – (some sufferers vomit up food they ate quite a while ago)
  • Irritability
  • Euphoria
  • Food cravings
  • Constipation
  • Diarrhea
  • Sensitivity to odors, noise and light
  • Increased urination

Physicians who specialize in migraine treatment find that only 30% of sufferers recognize that they have one or more of the “prodrome” symptoms until they are actually told what symptoms to look for. Once informed then up to 80% of sufferers report having one or more of them.

The Aura Stage – Less than half of migraine sufferers experience the aura stage. During this stage, about one-third of patients see flashing lights, wavy lines and blank spots in their field of vision (called scotoma) for a few minutes to a few hours before the pain stage begins. Some also have temporary trouble speaking or feel tingling or numbness on one side of the face or feet. (called parathesias). Others may develop a hypersensitivity to touch.

The Pain Stage – The onset of the pain stage can start within minutes or sometimes hours of the commencement of the aura stage. In addition to pain, nausea, vomiting, sensitivity to light (photophobia) sound (phonophobia) and movement may also be experienced.

The Postdrome Stage – During this stage of migraine, even though the pain is gone, some sufferers can feel exhausted, depressed and/or, residual neck pain.

What to try when you notice any of the symptoms in either the “prodrome” or “aura” phases.

If you haven’t realized it already, it is advantageous to experience either or both of these stages because they can both serve as a type of “advanced warning” system that a migraine is imminent.

It is to your advantage to try to address preventing your migraine as early as possible, so focus on the 13 symptoms listed in the prodromal section.

If you don’t experience any of these, but do experience the symptoms listed in the “aura” section, then that’s when you can start trying the following techniques to prevent your migraine from occurring:

TECHNIQUES TO TRY:  (None of these techniques work for everybody. You will need to experiment to see which of them help you the most.)

1-   H2O – Drink plenty of room temperature water to make sure you are well hydrated.

2-   BREATHE  – If you feel stressed, try meditating if you know how, or try these breathing exercises:

Stress Reducing-Breathing:
The depth and rate of our breathing respectively decrease and increase when we are stressed. This can deplete oxygen flow to the body and the brain. Please do this breathing exercise exactly as it is described at least 3 times a day:

Blow your breath out through your mouth and then seal your lips. Breathe in slowly through your nose for 10 seconds while expanding your chest. Hold it for 30 seconds while trying to think about “nothing”.

At the end of 30 seconds then slowly expel the breath you were holding, through your lips over a 15 second interval. Notice how your entire body relaxes throughout this breathing exercise especially during the exhalation segment.

Repeat this sequence at least 3 times in a row, working yourself up do doing it 5X in a row, three times a day.

Over time, as your body and brain relax and get used to this very effective breathing technique, you may want to increase the time you breathe in through you nose to 15 seconds, the time you hold your breath to 60 seconds and the time you exhale through your mouth to 30 seconds

Perhaps have someone massage you (if massage relaxes you.) Try taking a warm (not hot or cold) bath.

3-   ESSENTIAL OILS – Try applying either essential oils of peppermint or lavender to your temples, forehead and or neck. 2-3 drops is sufficient.  The side of the neck behind and below the ear is a good spot.

4-   IBUPROFEN – I am hesitant to suggest you consider taking any OTC or prescription medicines for pain based upon the symptoms of the prodrome phase because I don’t want people to medicate unnecessarily. (If you are pretty sure that one of the prodrome symptoms is a reliable indication that you are going to get a migraine that would be an exception).  But I do suggest trying either of these meds if you experience the symptoms of the aura phase.  I have seen just 200-400 mg of Ibuprofen help many people not only eliminate the aura but prevent the migraine too. (Of course you should confirm that it is OK taking any medication with your physician.)

5-    INCREASE MIGRELIEF DOSE – Though not clinically substantiated, anecdotal reports of MigreLief users taking an extra pill or two upon noticing any of the symptoms, have reported some benefits.  This is not totally surprising because a few studies have shown both feverfew and magnesium to not only prevent migraines but actually help to eliminate the pain of some migraines.

6-    GET OFF THE COMPUTER – Stop working on your computer.  The flickering or flashing lights of a computer screen is a trigger to some migraine sufferers.

7-   WALK –  If it’s not too hot or cold, get out and take a walk at a moderate pace for 10 minutes.

Please remember that none of the above suggestions works for everyone. You will have to experiment to see if one or more of these techniques works for you.

To learn more about successful migraine prevention, visit

Curt Hendrix M.S. C.C.N. C.N.S.



FDA Warning: Anti-Depressants and Migraine Prescription Drugs

July 20th, 2012

FDA Warns on Mixing Antidepressants with Migraine Drugs (First released in 2010)

ROCKVILLE, Md., July 20 — Mixing common migraine drugs with antidepressants can trigger a life-threatening condition called serotonin-syndrome, the FDA has warned.

Serotonin-syndrome is characterized by rapid heart beat, sudden changes in blood pressure, and increased body temperature. Other symptoms include restlessness, hallucinations, loss of coordination, overactive reflexes, nausea, vomiting, and diarrhea.

Options successful at preventing the occurrence of migraines would decrease the risk described above in patients taking anti-depressant and experiencing migraines.  

For warning signs of serotonin syndrome and more info on Anti-depressants and migraine drugs click on the link at the end of this article.  For information on your natural migraine control option recommended by doctors, neurologists and pharmacists, go to

MigreLief is a dietary supplement for the nutritional support of cerebrovascular function in migraine sufferers age 2 years and above.



Migraine Diary & Trigger Tracker from MigreLief

May 29th, 2012

Track and manage your migraines – before they manage you.

Click here to download your Migraine Diary

Note:  MigreLief can be taken by itself or combined with prescription migraine medications.  The MigreLief Migraine Diary is a great tool when starting MigreLief’s Triple Therapy for the first time.  If you record your daily intake of MigreLief and other medications, you may notice you soon have less of a need for your prescription drugs.

MigreLief addresses the underlying nutritional deficiencies and imbalances that migraine sufferers often have in common. More on MigreLief’s three mechanisms of action.