MigreLief-NOW

At last - a fast acting nutritional option for migraines!


Cerevasc Ginger is MigreLief-NOW’s proprietary blend of two ginger sources.  Ginger has been used as an ethnobotanical for hundreds of years. Now even conventional, allopathic clinicians and researchers are starting to recognize its medicinal benefits.  Ginger contains more than 200 substances in its oils, which is why it has so many different uses.  Ginger’s significant anti-inflammatory benefits have led to many clinical studies supporting its use.

Specific compounds in ginger are thought to be responsible for much of ginger’s beneficial activities. Trying to extract ginger to maximize these compounds could be beneficial but may also disrupt the balance of other ginger compounds that we are either not aware of or don’t understand as well.

We wanted to make sure that all of the naturally occurring ginger compounds are present in MigreLief-NOW.  Therefore, similarly to Puracol Feverfew, Akeso chose to include both a specific ginger powder and combine it with a specific proprietary ginger extract, and thus created Cerevasc ginger.  This assures both the proper ratios and quantities of those naturally occurring phytochemical in ginger that we believe are responsible for it multiple health benefits.

Akeso Health Sciences has worked hard to gain an understanding of how the compounds in ginger work, which ones are most potent and beneficial and is filing patents on methods to maximize the presence and ratios of the naturally occurring compounds.

Aflapin Boswellia Serrata Extract – A proprietary licensed nutraceutical containing Boswellia extract from Laila Pharmaceuticals of India, has been shown in clinical studies to have great health benefits.  The active ingredients are referred to as boswellic acids, with beta boswellic acid being the major component. The absorption of boswellic acids is less than ideal, thereby necessitating processing regimens that enhance their absorption. Until the advent of Aflapin due to poor absorption of the active boswellic acids, doses of 500-1,500 mg/day were necessary to achieve sufficient analgesic relief.  Because of the patented processing of Aflapin the therapeutic dose is down to 100-200 mg/day and compared to standard boswellia products, has been shown to be superior.

Boswellia is one of the true go to herbals medicines used by Ayurvedic physicians and now recent clinical studies are confirming what has been known for over 500 years in India.

Feverfew (Tanacetum parthenium) – Commonly recommended for its ability to support cerebrovascular tone, feverfew (Tanacetum parthenium) is rich in compounds known as sesquiterpene lactones. One of the more important of these compounds may be parthenolide, which represents 85% of the sesquiterpene lactone content in feverfew. Some scientific studies indicate that while parthenolide may be important there may very well be other phytochemicals in feverfew that are as of yet unidentified and play a role in its effectiveness for migraines.(1-10) Some studies of extracts of feverfew containing higher parthenolide levels yielded no significant benefits. This led researchers to believe that certain of the unidentified phytochemicals may have been left behind during the extraction process. The ideal solution would be combination of specific feverfew extract and whole leaf source that contained high levels of parthenolide yet kept all of the other naturally occurring phytochemicals as well, some of which may be eliminated in an extracted product.   Thus, Puracol Feverfew (AKESO HEALTH SCIENCE’S proprietary feverfew source) was developed. Puracol Feverfew, is just one of the reasons for the superior benefits of MigreLief. Akeso is a leader in feverfew research and is working to further elucidate the mechanisms of action of feverfew in the near future.

Magnesium – Research studies show that almost half of all migraine sufferers have low blood levels of magnesium – which is critical in controlling vasospasms (the contraction and dilation of blood vessels in the brain which occurs during migraines).

Magnesium is a nutritional supplement with numerous effects that support cerebrovascular tone.  These include: 1) inhibition of platelet aggregation; 2) interference with synthesis, release, and action of inflammatory mediators; 3) direct alterations of cerebrovascular tone; 4) inhibition of vasospasm; and 5) stabilization of cell membranes. Some migraine sufferers with poor cerebrovascular tone have been found to have low brain levels of magnesium.(11-16) Recommended daily dosages of magnesium typically range from 360 to 600 mg to compensate for this deficiency — far above what’s found in most multi-vitamins.

CLINICAL STUDIES:  Ginger, Boswellia, Feverfew and Magnesium